Zebrafish genomics: from mutants to genes

JH Postlethwait, WS Talbot - Trends in Genetics, 1997 - cell.com
Exquisite embryonic lethal mutations have been isolated in hundreds of genes necessary for
zebrafish development. Analysis of this resource promises to enhance our understanding of …

[HTML][HTML] Zebrafish genetics: mutant cornucopia

PD Currie - Current Biology, 1996 - cell.com
Zebrafish genetics: Mutant cornucopia: Current Biology Skip to Main Content Advertisement
Current Biology This journal offers authors two options (open access or subscription) to publish …

Zebrafish mutations and functional analysis of the vertebrate genome

WS Talbot, N Hopkins - Genes & development, 2000 - genesdev.cshlp.org
As the first draft of the human genome nears completion, we are faced with the challenge of
defining the functions of the 70,000–100,000 genes contained within the sequence. A …

Zebrafish: Genomics on the fast track

DR Beier - Genome research, 1998 - genome.cshlp.org
The zebrafish (Danio rerio) has proven its worth as an excellent model system for the study
of vertebrate development. In 1996, in an issue of the journal Development, the results of the …

Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development

G Golling, A Amsterdam, Z Sun, M Antonelli… - Nature …, 2002 - nature.com
To rapidly identify genes required for early vertebrate development, we are carrying out a
large-scale, insertional mutagenesis screen in zebrafish, using mouse retroviral vectors as …

Genetic and genomic tools for zebrafish research: the NIH zebrafish initiative

RS Rasooly, D Henken, N Freeman… - … dynamics: an official …, 2003 - Wiley Online Library
Abstract The National Institutes of Health (NIH) has been a leading advocate of the zebrafish
as a model organism for the study of vertebrate development, physiology, and disease …

Zebrafish genetics and its implications for understanding vertebrate development

PW Ingham - Human molecular genetics, 1997 - academic.oup.com
The identification of genes via their mutant phenotypes is the most direct way of dissecting
the molecular basis of developmental processes. While this approach has been extremely …

Zebrafish: bridging the gap between development and disease

A Dodd, PM Curtis, LC Williams… - Human molecular …, 2000 - academic.oup.com
The zebrafish has been the model of choice amongst developmental biologists for many
years. This small freshwater species offers many advantages to the study of organ and …

Transgenic zebrafish

S Lin - Developmental Biology Protocols: Volume II, 2000 - Springer
The zebrafish has become a popular model system for genetic studies of vertebrate
development. Zebrafish are amenable to such studies because the generation time of …

Transgenes as screening tools to probe and manipulate the zebrafish genome

A Amsterdam, TS Becker - Developmental dynamics: an official …, 2005 - Wiley Online Library
The zebrafish, originally an object of study as an inexpensive and prolific vertebrate
embryological model with a plethora of genetic tricks, has over the past decade moved to …