Down-regulation of microRNA-223 promotes degranulation via the PI3K/Akt pathway by targeting IGF-1R in mast cells

Q Wang, DY Zhao, H Xu, H Zhou, QY Yang, F Liu… - PloS one, 2015 - journals.plos.org
Background Mast cells play a central role in allergic and inflammatory disorders by inducing
degranulation and inflammatory mediator release. Recent reports have shown that miRNAs …

miR-99a regulates CD4+ T cell differentiation and attenuates experimental autoimmune encephalomyelitis by mTOR-mediated glycolysis

Y Gu, H Zhou, H Yu, W Yang, B Wang, F Qian… - … Therapy-Nucleic Acids, 2021 - cell.com
Multiple microRNAs exhibit diverse functions to regulate inflammatory and autoimmune
diseases. MicroRNA-99a (miR-99a) has been shown to be involved in adipose tissue …

MicroRNAs and potential target interactions in psoriasis

JR Zibert, MB Løvendorf, T Litman, J Olsen… - Journal of …, 2010 - Elsevier
BACKGROUND: Psoriasis is a chronic inflammatory skin disease often seen in patients with
a genetic susceptibility. MicroRNAs (miRNA) are endogenous, short RNA molecules that …

MicroRNA-24 Modulates Staphylococcus aureus-Induced Macrophage Polarization by Suppressing CHI3L1

Z Jingjing, Z Nan, W Wei, G Qinghe, W Weijuan… - Inflammation, 2017 - Springer
Macrophages play a crucial role in host innate anti-Staphylococcus aureus defense, which
is tightly regulated by multiple factors, including microRNAs. A recent study showed that miR …

MicroRNA‐21 and MicroRNA‐125b expression in skin tissue and serum as predictive biomarkers for psoriasis

SF Saadawy, MI El‐Ghareeb… - International journal of …, 2024 - Wiley Online Library
Background/objective Psoriasis is a chronic, inflammatory, and hyperproliferative skin
disease. We have investigated the role of miR‐21 and miR‐125b in the development of …

Increased serum miR-300 level serves as a potential biomarker of lipopolysaccharide-induced lung injury by targeting IκBα

W Cao, H Dai, S Yang, Z Liu… - Die Pharmazie-An …, 2017 - ingentaconnect.com
MicroRNAs (miRs) are reported to play key roles in various disease models. In this study, the
functional role of miR-300 in the regulation of lung injury was explored to assess the …

MicroRNA-766-3p contributes to anti-inflammatory responses through the indirect inhibition of NF-κB signaling

K Hayakawa, M Kawasaki, T Hirai, Y Yoshida… - International journal of …, 2019 - mdpi.com
MicroRNA (miRNA) is small RNA of 20 to 22 nucleotides in length and is stably present in
plasma. Regulating the expression of miRNA taken into cells has been suggested as a …

miR-802 participates in the inflammatory process of inflammatory bowel disease by suppressing SOCS5

J Yao, R Gao, M Luo, D Li, L Guo, Z Yu… - Bioscience …, 2020 - portlandpress.com
The present study aims to reveal the detailed molecular mechanism of microRNA (miR)-802
in the progression of inflammatory bowel disease (IBD). IBD tissues were obtained from IBD …

Circulating microRNA profile unveils mechanisms of action of acitretin for psoriasis vulgaris

L Chen, J Li, Y Yao, S Wang, S Zheng, X Ju… - …, 2021 - Taylor & Francis
Psoriasis vulgaris is a common chronic and recurrent inflammatory skin disease. In clinical
practice, acitretin is the first-line treatment drug for psoriasis vulgaris. MicroRNAs (miRNAs) …

miR-369-3p modulates inducible nitric oxide synthase and is involved in regulation of chronic inflammatory response

V Scalavino, M Liso, E Cavalcanti, I Gigante… - Scientific Reports, 2020 - nature.com
Dendritic cells are the most important antigen-presenting cells that link the innate and
acquired immune system. In our previous study, we identified that the upregulation of miR …