Prostate cancer (PCa) is the most prevalent cancer, a significant contributor to morbidity and
a leading cause of cancer-related death in men in Western industrialized countries. In …

Background: Prostate cancer (PCa) harbors a myriad of genomic and epigenetic defects.
Cytosine methylation of CpG-rich promoter DNA is an important mechanism of epigenetic …

Prostate cancer (PC) is the most commonly diagnosed nonskin malignancy and the second
most common cause of cancer death among men in the United States. Epigenetics is the …

Epigenetic alterations contribute significantly to the development and progression of
prostate cancer, the most prevalent malignant tumor in males of Western industrialized …

Prostate cancer is the most common malignancy and the second leading cause of cancer
death among men in the United States. There are three well-established risk factors for …

Background The prostate gland is the most common site of cancer and the second leading
cause of cancer mortality in American men. It is well known that epigenetic alterations such …

Prostate cancer is the most common noncutaneous malignancy and the second leading
cause of cancer death among men in the United States. DNA methylation and histone …

Abstract Background Prostate cancer (PCa) has the highest incidence rates of cancers in
men in western countries. Unlike several other types of cancer, PCa has few genetic drivers …

Prostate cancer is one of the most frequent cancers in males in Western industrialized
countries. Its course is highly variable, from indolent to highly lethal. Genetic changes vary …

During cancer development and progression, tumor cells undergo abnormal epigenetic
modifications, including DNA methylation, histone deacetylation and nucleosome …