After briefly reviewing the nature of DNA methylation, its general role in cancer and the tools
available to interrogate it, we consider the literature surrounding DNA methylation as …

Many differentially methylated genes have been identified in prostate cancer (PCa),
primarily using candidate gene-based assays. Recently, several global DNA methylation …

Prostate cancer is a highly prevalent malignancy, which is clinically silent but curable while
organ-confined. Because available screening methods show poor sensitivity and specificity …

The leading causes of death across the world are cancer, cardiovascular diseases and
chronic lower respiratory diseases, cerebrovascular diseases, Alzheimer's disease, diabetes …

The importance of epigenetic processes in the development of cancer is clear. The study of
epigenetics is therefore bound to contribute to the improvement of human health …

Prostate cancer is one of the most common non-cutaneous malignancies among men
worldwide. Epigenetic aberrations, including changes in DNA methylation patterns and/or …

Only a part of prostate cancer (PCa) patients has aggressive malignancy requiring adjuvant
treatment after radical prostatectomy (RP). Biomarkers capable to predict biochemical PCa …

DNA methylation, copy number in the genomes of three immortalized prostate epithelial, five
cancer cell lines (LNCaP, PC3, PC3M, PC3M-Pro4, PC3MLN4) were compared using a …

Prostate cancer (PCa) is the most prevalent urological cancer that affects aging men in
South Africa, and mechanisms underlying prostate tumorigenesis remain elusive. Research …

BACKGROUND In prostate cancer (PCa), abnormal expression of several microRNAs
(miRNAs) has been previously reported. Increasing evidence shows that aberrant …