Aims Carnitine and choline are major nutrient precursors for gut microbiota-dependent
generation of the atherogenic metabolite, trimethylamine N-oxide (TMAO). We performed …

Scope Trimethylamine‐N‐oxide (TMAO), a metabolite linked to the gut microbiota, is
associated with excess risk of heart disease. We hypothesized that (i) TMAO response to …

Background: Trimethylamine-N-oxide (TMAO), a choline-derived gut microbiota-dependent
metabolite, is a newly recognized risk marker for cardiovascular disease. We sought to …

ABSTRACT Background Trimethylamine-N-oxide (TMAO), a diet-derived and gut microbiota–
related metabolite, is associated with cardiovascular disease (CVD). However, major dietary …

The gut microbiota plays an obligatory role in the metabolism of nutrients containing
trimethylamine moieties, such as l-carnitine and choline, leading to the production of the …

ABSTRACT Background Trimethylamine N-oxide (TMAO), a diet-derived, gut microbial-host
cometabolite, has been linked to cardiometabolic diseases. However, the relations remain …

Objectives Gut-produced trimethylamine N-oxide (TMAO) is postulated as a possible link
between red meat intake and poor cardiometabolic health. We investigated whether gut …

Background Dietary nutrient intake and its metabolism by the gut microbiome have recently
been implicated in cardiovascular disease (CVD) risk. In particular, trimethylamine N-oxide …

Background Trimethylamine N‐oxide (TMAO) is a gut microbiota‐dependent metabolite of
dietary choline, L‐carnitine, and phosphatidylcholine‐rich foods. On the basis of …

Background Recent studies show a mechanistic link between gut microbiota-dependent
formation of the atherosclerosis-and thrombosis-promoting metabolite trimethylamine N …