Background—DNA methylation leaves a long-term signature of smoking exposure and is
one potential mechanism by which tobacco exposure predisposes to adverse health …

We conducted a genome-wide association study of blood DNA methylation and smoking,
attempted replication of previously discovered associations, and assessed the reversibility of …

Background Multiple studies have made robust associations between differential DNA
methylation and exposure to cigarette smoke. But whether a DNA methylation phenotype is …

Background: Smoking-associated DNA methylation levels identified through epigenome-
wide association studies (EWASs) are generally ascribed to smoking-reactive mechanisms …

Background The evidence for epigenome-wide associations between smoking and DNA
methylation continues to grow through cross-sectional studies. However, few large-scale …

Environmental factors such as tobacco smoking may have long-lasting effects on DNA
methylation patterns, which might lead to changes in gene expression and in a broader …

DNA methylation is the most studied epigenetic modification, capable of controlling gene
expression in the contexts of normal traits or diseases. It is highly dynamic during early …

Background Epigenome-wide profiling of DNA methylation pattern with respect to tobacco
smoking has given rise to a new measure of smoking exposure. We investigated the …

Active smoking is a major preventable public health problem and an established critical
factor for epigenetic modification. In this systematic review, we identified 17 studies …

Aim: Epigenetic changes may occur in response to environmental stressors, and an altered
epigenome pattern may represent a stable signature of environmental exposure. Materials & …