[HTML][HTML] Theaflavin-3, 3'-digallate decreases human ovarian carcinoma OVCAR-3 cell-induced angiogenesis via Akt and Notch-1 pathways, not via MAPK pathways

Y Gao, GO Rankin, Y Tu… - … journal of oncology, 2016 - spandidos-publications.com
Abstract Theaflavin-3, 3'-digallate (TF3) is a black tea polyphenol produced from
polymerization and oxidization of the green tea ployphenols epicatechin gallate and (-) …

Inhibitory effects of the four main theaflavin derivatives found in black tea on ovarian cancer cells

Y Gao, GO Rankin, Y Tu, YC Chen - Anticancer research, 2016 - ar.iiarjournals.org
Background: Some polyphenols induce apoptosis and inhibit angiogenesis. Consumption of
black tea, rich in polyphenols, has been found to reduce ovarian cancer risk. Theaflavin …

Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1α pathway

LZ Liu, Y Jing, LL Jiang, XE Jiang, Y Jiang… - Biochemical and …, 2011 - Elsevier
Acacetin (5, 7-dihydroxy-4′-methoxyflavone) is a flavone compound, some of which have
anti-cancerous effects. Vascular endothelial growth factor (VEGF) plays an important role in …

Theaflavin‐3, 3′‐digallate induces epidermal growth factor receptor downregulation

H Mizuno, YY Cho, F Zhu, WY Ma… - … in cooperation with …, 2006 - Wiley Online Library
Black tea is one of the most popular beverages worldwide and especially in Western
nations. Theaflavins, a mixture of theaflavin (TF‐1), theaflavin‐3‐gallate (TF‐2a), theaflavin …

Dietary compounds galangin and myricetin suppress ovarian cancer cell angiogenesis

H Huang, AY Chen, Y Rojanasakul, X Ye… - Journal of functional …, 2015 - Elsevier
Galangin and myricetin are flavonoids isolated from vegetables and fruits which exhibit anti-
proliferative activity in human cancer cells. In this study, their anti-angiogenic effects were …

Theaflavin-3, 3′-digallate inhibits ovarian cancer stem cells via suppressing Wnt/β-Catenin signaling pathway

H Pan, E Kim, GO Rankin, Y Rojanasakul, Y Tu… - Journal of functional …, 2018 - Elsevier
Recent evidence indicates that ovarian cancer stem cells (CSCs) are responsible for ovarian
cancer recurrence and drug resistance, resulting in the low long-term survival rate of …

Amentoflavone induces anti-angiogenic and anti-metastatic effects through suppression of NF-κB activation in MCF-7 cells

JH Chen, WL Chen, YC Liu - Anticancer Research, 2015 - ar.iiarjournals.org
The aim of the present study was to investigate whether amentoflavone induces anti-
angiogenic and anti-metastatic effects through suppression of NF-κB activation in breast …

[HTML][HTML] EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression

JW Gu, KL Makey, KB Tucker, E Chinchar, X Mao, I Pei… - Vascular cell, 2013 - Springer
The role of EGCG, a major green tea catechin in breast cancer therapy is poorly understood.
The present study tests the hypothesis that EGCG can inhibit the activation of HIF-1α and …

Amentoflavone suppresses tumor growth in ovarian cancer by modulating Skp2

H Liu, Q Yue, S He - Life sciences, 2017 - Elsevier
Aim Ovarian cancer is one of most common malignancies in women and is associated with
high reoccurrence rate and poor prognosis. This study is designed to investigate the anti …

[HTML][HTML] Theaflavin-3, 3′-digallate suppresses human ovarian carcinoma OVCAR-3 cells by regulating the checkpoint kinase 2 and p27 kip1 pathways

Y Gao, J Yin, Y Tu, YC Chen - Molecules, 2019 - mdpi.com
Theaflavin-3, 3′-digallate (TF3) is a unique polyphenol in black tea. Epidemiological
studies have proved that black tea consumption decreases the incidence rate of ovarian …