Dynamics of DNA methylation during development
M Brandeis, M Ariel, H Cedar - Bioessays, 1993 - Wiley Online Library
DNA methylation plays a role in the repression of gene expression in animal cells. In the
mouse preimplantation embryo, most genes are unmethylated but a wave of de novo …
mouse preimplantation embryo, most genes are unmethylated but a wave of de novo …
DNA methylation and embryogenesis
A Razin, H Cedar - DNA methylation: molecular biology and biological …, 1993 - Springer
A large number of studies have documented the methylation patterns of individual genes
and repeated sequences in different tissues of various mammalian species. This has …
and repeated sequences in different tissues of various mammalian species. This has …
DNA methylation in early development
A Razin, R Shemer - Human Molecular Genetics, 1995 - academic.oup.com
Several lines of evidence strongly suggest that DNA methylation is involved in embryo
development. Perhaps the most direct evidence comes from experiments with …
development. Perhaps the most direct evidence comes from experiments with …
Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line.
Methylation patterns of specific genes have been studied by polymerase chain reaction and
found to undergo dynamic changes in the germ line and early embryo. Some CpG sites are …
found to undergo dynamic changes in the germ line and early embryo. Some CpG sites are …
Mechanistic aspects of genome-wide demethylation in the preimplantation mouse embryo.
T Kafri, X Gao, A Razin - Proceedings of the National …, 1993 - National Acad Sciences
Gene-specific methylation patterns in mammals play a role in a variety of biological
processes in the embryo and adult tissues. These patterns are established during embryo …
processes in the embryo and adult tissues. These patterns are established during embryo …
Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development
M Monk, M Boubelik, S Lehnert - Development, 1987 - journals.biologists.com
This paper shows stage-and tissue-specific global demethylation and remethylation
occurring during embryonic development. The egg genome is strikingly undermethylated …
occurring during embryonic development. The egg genome is strikingly undermethylated …
Epigenetic programming of differential gene expression in development and evolution
M Monk - Developmental genetics, 1995 - Wiley Online Library
This review covers data on changing patterns of DNA methylation and the regulation of gene
expression in mouse embryonic development. Global demethylation occurs from the eight …
expression in mouse embryonic development. Global demethylation occurs from the eight …
Dynamic reprogramming of DNA methylation in the early mouse embryo
Dynamic epigenetic modification of the genome occurs during early development of the
mouse. Active demethylation of the paternal genome occurs in the zygote, followed by …
mouse. Active demethylation of the paternal genome occurs in the zygote, followed by …
[HTML][HTML] Formation of methylation patterns in the mammalian genome
MS Turker, TH Bestor - Mutation Research/Reviews in Mutation Research, 1997 - Elsevier
Cytosine methylation in mammals is an epigenetic modification required for viability of the
developing embryo. It has been suggested that DNA methylation plays important roles in X …
developing embryo. It has been suggested that DNA methylation plays important roles in X …
DNA methylation in mammalian development and disease
W Dean, D Lucifero, F Santos - Birth Defects Research Part C …, 2005 - Wiley Online Library
Epigenetic modification of the cytosine base of DNA by its methylation introduced the
possibility that beyond the inherent information contained within the nucleotide sequence …
possibility that beyond the inherent information contained within the nucleotide sequence …
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