Objective Birth asphyxia (BA) is often associated with seizures that may exacerbate the
ensuing hypoxic–ischemic encephalopathy. In rodent models of BA, exposure to hypoxia is …

Objective Seizures are more common in the neonatal period than at any other stage of life.
Phenobarbital is the first‐line treatment for neonatal seizures and is at best effective in …

Basal ganglia injury after hypoxia-ischemia remains common in preterm infants, and is
closely associated with later cerebral palsy. In the present study we tested the hypothesis …

Current first-line drugs for the treatment of neonatal seizures have limited efficacy and are
associated with side effects. Uncontrolled seizures may exacerbate brain injury and …

Hypoxic ischemic encephalopathy after perinatal asphyxia is a major cause of mortality and
morbidity in infants. Here, we evaluated pathologic changes in the hippocampi of a cohort of …

OBJECTIVE: To examine whether neonatal seizures are associated with
neurodevelopmental outcomes in infants with hypoxia-ischemia independent of the …

Objective To evaluate the association between sedation–analgesia (SA) during initial 72 h
and death/disability at 18 months of age in neonatal hypoxic-ischemic encephalopathy …

Exposure to hypoxic-ischaemia (HI) is consistently followed by a delayed fall in cerebral
perfusion. In preterm fetal sheep this is associated with impaired cerebral oxygenation …

The acute and long-term consequences of perinatal asphyxia have been extensively
investigated, but only a few studies have focused on postnatal asphyxia. In particular …

Perinatal hypoxic-ischemic encephalopathy (HIE) is a major cause of acute mortality and
chronic neurologic morbidity in infants and children. HIE is the most common cause of …