DNA methylation is an important epigenetic modification involved in many biological
processes and diseases. Many studies have mapped DNA methylation changes associated …

DNA methylation is a key functional regulatory mechanism in human genome, which plays
critical roles in development, differentiation and many diseases. With rapid progress of large …

As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types …

In mammals, DNA methylation is a crucial epigenetic modification with key functions during
development. Cellular processes that are regulated by DNA methylation comprise X …

Although single base-pair resolution DNA methylation landscapes for embryonic and
different somatic cell types provided important insights into epigenetic dynamics and cell …

DNA methylation has been proved to play important roles in cell development and complex
diseases through comparative studies of DNA methylation profiles across different tissues …

Background DNA epigenetic modifications, such as methylation, are important regulators of
tissue differentiation, contributing to processes of both development and cancer. Profiling the …

Despite numerous studies done on understanding the role of DNA methylation, limited work
has focused on systems integration of cell type-specific interplay between DNA methylation …

DNA methylation is a fundamental epigenetic mark that governs chromatin organization, cell
identity, and gene expression. Here we describe a human methylome atlas, based on deep …

Background DNA methylation is a major epigenetic modification important for regulating
gene expression and suppressing spurious transcription. Most methods to scan the genome …