Intrahepatic cholangiocarcinoma (iCCA) is an aggressive malignancy with increasing
incidence. It has been suggested that DNA methylation drives cancer development …

Background Cholangiocarcinoma (CCA) is a rare disease, but it is amongst the most lethal
cancers with a median survival under 1 year. Variations in DNA methylation and gene …

Background Cholangiocarcinoma (CCA) is a subtype of highly malignant hepatic tumor,
which has low 5-year survival rate and poor clinical outcome. Only a few patients can be …

Background The incidence of cholangiocarcinoma (CCA) has risen in recent years, and it
has become a significant health burden worldwide. However, the mechanisms underlying …

Intrahepatic cholangiocarcinoma (iCCA) is the second most prevalent primary liver cancer.
Although the genetic characterization of iCCA has led to targeted therapies for treating …

Background: Methylation plays a significant role in the etiology and pathogenesis of
hepatocellular carcinoma (HCC). The aim of the present study is to identify aberrantly …

The molecular mechanisms underlying the genesis of cholangiocarcinomas (CCs) are
poorly understood. Epigenetic changes such as aberrant hypermethylation and subsequent …

Cholangiocarcinoma (CCA) is the most common primary liver cancer in Northeastern
Thailand where liver fluke infection is highly endemic. Although aberrant DNA methylation in …

Background In recent years, DNA methylation modification has been shown to be a critical
mechanism in the field of epigenetics. Methods Hepatocellular carcinoma (HCC) data were …

Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the two
most common pathology subtypes of primary liver cancer (PLC). Identifying DNA methylation …