[HTML][HTML] ACE DD genotype: a predisposing factor for abdominal aortic aneurysm

C Fatini, G Pratesi, F Sofi, F Gensini, E Sticchi… - European journal of …, 2005 - Elsevier
OBJECTIVE: To examine the role of polymorphisms in angiotensin converting enzyme (ACE,
I/D) and angiotensin II receptor (AT1R, A1166C) in the development of abdominal aortic …

Abdominal aortic aneurysm in normotensive patients: association with angiotensin-converting enzyme gene polymorphism

R Pola, E Gaetani, A Santoliquido, L Gerardino… - European Journal of …, 2001 - Elsevier
Objective and Design to assess if deletion of the angiotensin-converting enzyme (ACE)
gene is a risk factor for abdominal aortic aneurysms (AAAs) in normotensive patients …

Angiotensin-converting enzyme (ACE, I/D) gene polymorphism and susceptibility to abdominal aortic aneurysm or aortoiliac occlusive disease

A Korcz, J Mikołajczyk-Stecyna, M Gabriel… - Journal of Surgical …, 2009 - Elsevier
BACKGROUND: The purpose of this study was to examine the role of polymorphism in
angiotensin converting enzyme gene (ACE, I/D) in the development of abdominal aortic …

Deletion polymorphism in the gene for angiotensin-converting enzyme is not a risk factor predisposing to abdominal aortic aneurysm

K Hamano, M Ohishi, M Ueda, K Fujioka… - European journal of …, 1999 - Elsevier
Objective: to establish whether deletion of the angiotensin-converting enzyme (ACE) gene is
a risk factor predisposing to abdominal aortic aneurysm (AAA) or not. Methods: the study …

[HTML][HTML] Does the angiotensin-converting enzyme (ACE) gene polymorphism affect rate of abdominal aortic aneurysm expansion?

JMC Yeung, M Heeley, S Gray, MK Lingam… - European journal of …, 2002 - Elsevier
Objectives: the tissue renin-angiotensin system (RAS), which plays an important role in
vascular structure and function, is regulated in part by an insertion-deletion polymorphism of …

ACE and TGFBR1 genes interact in influencing the susceptibility to abdominal aortic aneurysm

L Lucarini, E Sticchi, F Sofi, G Pratesi, C Pratesi, R Pulli… - Atherosclerosis, 2009 - Elsevier
A role of ACE I/D polymorphism in the pathogenesis of abdominal aortic aneurysm (AAA)
has been demonstrated, possibly due to the effect of angiotensin II on vascular tissue …

Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohorts

GT Jones, AR Thompson… - … , and vascular biology, 2008 - Am Heart Assoc
Objectives—Although polymorphic variations in genes of the RAS system have previously
been associated with susceptibility to AAA, such studies have been significantly limited by …

[HTML][HTML] Angiotensin-converting enzyme insertion/deletion polymorphism is a risk factor for thoracic aortic aneurysm in patients with bicuspid or tricuspid aortic valves

I Foffa, M Murzi, M Mariani, AM Mazzone… - The Journal of Thoracic …, 2012 - Elsevier
OBJECTIVE: The angiotensin-converting enzyme (ACE) is highly expressed in the
aneurysmal vascular wall, in both animal models and human disease. Genetic variations in …

The genetics of abdominal aortic aneurysms: a comprehensive meta-analysis involving eight candidate genes in over 16,700 patients.

P McColgan, GE Peck, RM Greenhalgh… - International …, 2009 - europepmc.org
Abdominal aortic aneurysms (AAAs) are thought to be multifactorial in etiology. A variety of
susceptibility genes have been associated, but definitive conclusions have been difficult to …

[HTML][HTML] Analysis of multiple genetic polymorphisms in aggressive-growing and slow-growing abdominal aortic aneurysms

T Duellman, CL Warren, J Matsumura, J Yang - Journal of vascular surgery, 2014 - Elsevier
Background The natural history of abdominal aortic aneurysms (AAAs) suggests that some
remain slow in growth rate whereas many develop a more accelerated growth rate and …