Cerebral spinal fluid dynamics: effect of hypoxia and implications for high-altitude illness

JS Lawley, BD Levine, MA Williams… - Journal of Applied …, 2016 - journals.physiology.org
The pathophysiology of acute mountain sickness and high-altitude cerebral edema, the
cerebral forms of high-altitude illness, remain uncertain and controversial. Persistently …

AltitudeOmics: effect of ascent and acclimatization to 5260 m on regional cerebral oxygen delivery

AW Subudhi, JL Fan, O Evero… - Experimental …, 2014 - Wiley Online Library
New Findings What is the central question of this study? Hypoxia associated with ascent to
high altitude may threaten cerebral oxygen delivery. We sought to determine whether there …

Cognitive and neuroimaging changes in healthy immigrants upon relocation to a high altitude: a panel study

X Chen, Q Zhang, J Wang, J Liu, W Zhang… - Human Brain …, 2017 - Wiley Online Library
Background Cognitive and neuroimaging changes under chronic high‐altitude exposure
have never been followed up and dynamically assessed. Objectives To investigate the …

Effects of chronic hypoxic environment on cognitive function and neuroimaging measures in a high-altitude population

YQ Zhang, WJ Zhang, JH Liu, W Ji - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Objective This study aimed to investigate the effects of long-term hypoxic environment
exposure on cognitive ability and neuroimaging characteristics in a highland population in …

High altitude is associated with pTau deposition, neuroinflammation, and myelin loss

D Iacono, EK Murphy, PM Sherman, H Chapapas… - Scientific reports, 2022 - nature.com
Mammals are able to adapt to high altitude (HA) if appropriate acclimation occurs. However,
specific occupations (professional climbers, pilots, astronauts and other) can be exposed to …

[HTML][HTML] Altitude stress during participation of medical congress

SB Kim, JS Kim, SJ Kim, SH Cho… - Neurointervention, 2016 - synapse.koreamed.org
Medical congresses often held in highlands. We reviewed several medical issues
associated with altitude stress especially while physicians have participated medical …

Hypobaric hypoxic cerebral insults: the neurological consequences of going higher

EH Maa - NeuroRehabilitation, 2010 - content.iospress.com
As increasing numbers of people live, work, and play at high altitudes, awareness of the
neurological consequences of hypobaric hypoxic environments becomes paramount …

HSP‐70‐Mediated Hyperbaric Oxygen Reduces Brain and Pulmonary Edema and Cognitive Deficits in Rats in a Simulated High‐Altitude Exposure

HH Wu, KC Niu, CH Lin, HJ Lin… - BioMed Research …, 2018 - Wiley Online Library
High‐mountain sickness is characterized by brain and pulmonary edema and cognitive
deficits. The definition can be fulfilled by a rat model of high‐altitude exposure (HAE) used in …

Normobaric hypoxia and symptoms of acute mountain sickness: elevated brain volume and intracranial hypertension

JS Lawley, N Alperin, AM Bagci, SH Lee… - Annals of …, 2014 - Wiley Online Library
Objective The study was undertaken to determine whether normobaric hypoxia causes
elevated brain volume and intracranial pressure in individuals with symptoms consistent …

Effects of long-term exposure to high altitude on brain structure in healthy people: an MRI-based systematic review and meta-analysis

Q Luo, JX Zhang, S Huang, YH Hu, H Wang… - Frontiers in …, 2023 - frontiersin.org
Purpose To conduct a systematic review and meta-analysis of observational studies of brain
MRI, this paper assesses the effects of long-term exposure to high-altitude on brain …