DNA methylation landscapes: provocative insights from epigenomics

MM Suzuki, A Bird - Nature reviews genetics, 2008 - nature.com
The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine.
To understand the biological significance of this epigenetic mark it is essential to know …

DNA methylation dynamics in health and disease

Y Bergman, H Cedar - Nature structural & molecular biology, 2013 - nature.com
DNA methylation is an epigenetic mark that is erased in the early embryo and then re-
established at the time of implantation. In this Review, dynamics of DNA methylation during …

DNA methylation: superior or subordinate in the epigenetic hierarchy?

B Jin, Y Li, KD Robertson - Genes & cancer, 2011 - journals.sagepub.com
Epigenetic modifications are heritable changes in gene expression not encoded by the DNA
sequence. In the past decade, great strides have been made in characterizing epigenetic …

Genomic patterns and context specific interpretation of DNA methylation

T Baubec, D Schübeler - Current opinion in genetics & development, 2014 - Elsevier
Methylation of CpG dinucleotides is a reversible modification of DNA that is highly prevalent
throughout mammalian genomes. Recent advances generated genomic DNA methylation …

DNA methylation dynamics in cellular commitment and differentiation

M Suelves, E Carrió, Y Núñez-Álvarez… - Briefings in functional …, 2016 - academic.oup.com
DNA methylation is an essential epigenetic modification for mammalian development and is
crucial for the establishment and maintenance of cellular identity. Traditionally, DNA …

Dynamics of DNA methylation pattern

CL Hsieh - Current opinion in genetics & development, 2000 - Elsevier
Methylation patterns are the result of de novo methylation, demethylation, and the
maintenance of existing methylation. Although the existence and identity of an active …

Staying true to yourself: mechanisms of DNA methylation maintenance in mammals

N Petryk, S Bultmann, T Bartke… - Nucleic acids …, 2021 - academic.oup.com
DNA methylation is essential to development and cellular physiology in mammals. Faulty
DNA methylation is frequently observed in human diseases like cancer and neurological …

Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes

Z Su, L Han, Z Zhao - Epigenetics, 2011 - Taylor & Francis
DNA methylation is one of the most important heritable epigenetic modifications of the
genome and is involved in the regulation of many cellular processes. Aberrant DNA …

[HTML][HTML] The cell biology of DNA methylation in mammals

E Prokhortchouk, PA Defossez - … et Biophysica Acta (BBA)-Molecular Cell …, 2008 - Elsevier
In this review, we will provide a brief reminder of epigenetic phenomena in general, and
DNA methylation in particular. We will then underline the characteristics of the in vivo …

New insights into mechanisms that regulate DNA methylation patterning

G Ficz - Journal of Experimental Biology, 2015 - journals.biologists.com
From a fertilised egg to a mature organism, cells divide and accumulate epigenetic
information, which is faithfully passed on to daughter cells. DNA methylation consolidates …