DNA methylation of FKBP5 and response to exposure‐based psychological therapy
Differential DNA methylation of the hypothalamic‐pituitary‐adrenal axis related gene FKBP5
has recently been shown to be associated with varying response to environmental …
has recently been shown to be associated with varying response to environmental …
Stress, burnout and depression: A systematic review on DNA methylation mechanisms
Despite that burnout presents a serious burden for modern society, there are no diagnostic
criteria. Additional difficulty is the differential diagnosis with depression. Consequently, there …
criteria. Additional difficulty is the differential diagnosis with depression. Consequently, there …
Epigenetic alterations in depression and antidepressant treatment
Epigenetic modifications control chromatin structure and function, and thus mediate changes
in gene expression, ultimately influencing protein levels. Recent research indicates that …
in gene expression, ultimately influencing protein levels. Recent research indicates that …
A methylation study of long-term depression risk
Recurrent and chronic major depressive disorder (MDD) accounts for a substantial part of
the disease burden because this course is most prevalent and typically requires long-term …
the disease burden because this course is most prevalent and typically requires long-term …
Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions
Although the fact that genetic predisposition and environmental exposures interact to shape
development and function of the human brain and, ultimately, the risk of psychiatric …
development and function of the human brain and, ultimately, the risk of psychiatric …
Life course socioeconomic status and DNA methylation in genes related to stress reactivity and inflammation: the multi-ethnic study of atherosclerosis
Epigenetic changes, such as DNA methylation, have been hypothesized to provide a link
between the social environment and disease development. The purpose of this study was to …
between the social environment and disease development. The purpose of this study was to …
Oxidative stress and DNA methylation regulation in the metabolic syndrome
S Yara, JC Lavoie, E Levy - Epigenomics, 2015 - Taylor & Francis
DNA methylation is implicated in tissue-specific gene expression and genomic imprinting. It
is modulated by environmental factors, especially nutrition. Modified DNA methylation …
is modulated by environmental factors, especially nutrition. Modified DNA methylation …
NR3C1 hypermethylation in depressed and bullied adolescents
P Efstathopoulos, F Andersson, PA Melas… - Translational …, 2018 - nature.com
The disruption of key epigenetic processes during critical periods of brain development can
increase an individual's vulnerability to psychopathology later in life. For instance, DNA …
increase an individual's vulnerability to psychopathology later in life. For instance, DNA …
Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and …
Epigenetic factors modify the effects of environmental factors on biological outcomes.
Identification of epigenetic changes that associate with PTSD is therefore a crucial step in …
Identification of epigenetic changes that associate with PTSD is therefore a crucial step in …
Cell type–specific methylome-wide association studies implicate neurotrophin and innate immune signaling in major depressive disorder
Background We sought to characterize methylation changes in brain and blood associated
with major depressive disorder (MDD). As analyses of bulk tissue may obscure association …
with major depressive disorder (MDD). As analyses of bulk tissue may obscure association …