A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip® for Methylome Profiling

C Clark, P Palta, CJ Joyce, C Scott, E Grundberg… - PloS one, 2012 - journals.plos.org
DNA methylation is one of the most studied epigenetic marks in the human genome, with the
result that the desire to map the human methylome has driven the development of several …

DNA methylation profiling: comparison of genome-wide sequencing methods and the Infinium Human Methylation 450 Bead Chip

DL Walker, AV Bhagwate, S Baheti, RL Smalley… - …, 2015 - Taylor & Francis
Aims: To compare the performance of four sequence-based and one microarray methods for
DNA methylation profiling. Methods: DNA from two cell lines were profiled by reduced …

Whole genome DNA methylation analysis based on high throughput sequencing technology

N Li, M Ye, Y Li, Z Yan, LM Butcher, J Sun, X Han… - Methods, 2010 - Elsevier
There are numerous approaches to decipher a whole genome DNA methylation profile
(“methylome”), each varying in cost, throughput and resolution. The gold standard of these …

[HTML][HTML] AutoMeDIP-seq: a high-throughput, whole genome, DNA methylation assay

LM Butcher, S Beck - Methods, 2010 - Elsevier
DNA methylation is an epigenetic mark linking DNA sequence and transcription regulation,
and therefore plays an important role in phenotypic plasticity. The ideal whole genome …

Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome

A Noguera-Castells, CA García-Prieto… - Epigenetics, 2023 - Taylor & Francis
ABSTRACT DNA methylation, one of the best characterized epigenetic marks in the human
genome, plays a pivotal role in gene transcription regulation and other biological processes …

Comparison of methylation capture sequencing and Infinium MethylationEPIC array in peripheral blood mononuclear cells

C Shu, X Zhang, BE Aouizerat, K Xu - Epigenetics & chromatin, 2020 - Springer
Background Epigenome-wide association studies (EWAS) have been widely applied to
identify methylation CpG sites associated with human disease. To date, the Infinium …

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

B Zhang, Y Zhou, N Lin, RF Lowdon, C Hong… - Genome …, 2013 - genome.cshlp.org
DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …

Usability of human Infinium MethylationEPIC BeadChip for mouse DNA methylation studies

M Needhamsen, E Ewing, H Lund… - BMC …, 2017 - Springer
Background The advent of array-based genome-wide DNA methylation methods has
enabled quantitative measurement of single CpG methylation status at relatively low cost …

Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison

T De Meyer, P Bady, G Trooskens, S Kurscheid… - Scientific reports, 2015 - nature.com
Two cost-efficient genome-scale methodologies to assess DNA-methylation are MethylCap-
seq and Illumina's Infinium HumanMethylation450 BeadChips (HM450). Objective …

Genome-Wide Dna Methylation Profiling Using Infinium® Assay

M Bibikova, J Le, B Barnes, S Saedinia-Melnyk… - …, 2009 - Taylor & Francis
Aims: Bisulfite sequence analysis of individual CpG sites within genomic DNA is a powerful
approach for methylation analysis in the genome. The major limitation of bisulfite-based …