Genome-wide association analysis identifies a genetic basis of infectivity in a model bacterial pathogen

JP Andras, PD Fields, L Du Pasquier… - Molecular biology …, 2020 - academic.oup.com
Abstract Knowledge of the genetic architecture of pathogen infectivity and host resistance is
essential for a mechanistic understanding of coevolutionary processes, yet the genetic basis …

Balancing selection for pathogen resistance reveals an intercontinental signature of Red Queen coevolution

Y Bourgeois, PD Fields, G Bento… - Molecular Biology and …, 2021 - academic.oup.com
The link between long-term host–parasite coevolution and genetic diversity is key to
understanding genetic epidemiology and the evolution of resistance. The model of Red …

Parasitism drives host genome evolution: Insights from the Pasteuria ramosaDaphnia magna system

Y Bourgeois, AC Roulin, K Müller, D Ebert - Evolution, 2017 - academic.oup.com
Because parasitism is thought to play a major role in shaping host genomes, it has been
predicted that genomic regions associated with resistance to parasites should stand out in …

Uncovering the genomic basis of infection through co-genomic sequencing of hosts and parasites

E Dexter, PD Fields, D Ebert - Molecular Biology and Evolution, 2023 - academic.oup.com
Understanding the genomic basis of infectious disease is a fundamental objective in co-
evolutionary theory with relevance to healthcare, agriculture, and epidemiology. Models of …

[HTML][HTML] Genetics and genomics of infectious diseases in key aquaculture species

NH Nguyen - Biology, 2024 - mdpi.com
Simple Summary Diseases pose a significant challenge for aquaculture, exacerbated by
changing weather conditions. The sector has explored various strategies, including …

Virulence evolution of pathogens that can grow in reservoir environments

A Pandey, N Mideo, TG Platt - The American Naturalist, 2022 - journals.uchicago.edu
Many pathogens reside in environmental reservoirs within which they can reproduce and
from which they can infect hosts. These facultative pathogens experience different selective …

[HTML][HTML] Transcriptome profiling during a natural host-parasite interaction

SJ McTaggart, T Cézard, JS Garbutt, PJ Wilson… - BMC genomics, 2015 - Springer
Background Infection outcome in some coevolving host-pathogens is characterised by host-
pathogen genetic interactions, where particular host genotypes are susceptible only to a …

[HTML][HTML] Transcriptomic Response to Perkinsus marinus in Two Crassostrea Oysters Reveals Evolutionary Dynamics of Host-Parasite Interactions

J Chan, L Wang, L Li, K Mu, D Bushek, Y Xu… - Frontiers in …, 2021 - frontiersin.org
Infectious disease outbreaks are causing widespread declines of marine invertebrates
including corals, sea stars, shrimps, and molluscs. Dermo is a lethal infectious disease of the …

[HTML][HTML] QTL study reveals candidate genes underlying host resistance in a Red Queen model system

M Fredericksen, PD Fields, L Du Pasquier, V Ricci… - PLoS …, 2023 - journals.plos.org
Specific interactions of host and parasite genotypes can lead to balancing selection,
maintaining genetic diversity within populations. In order to understand the drivers of such …

[HTML][HTML] Long-term balancing selection for pathogen resistance maintains trans-species polymorphisms in a planktonic crustacean

L Cornetti, PD Fields, L Du Pasquier, D Ebert - Nature Communications, 2024 - nature.com
Balancing selection is an evolutionary process that maintains genetic polymorphisms at
selected loci and strongly reduces the likelihood of allele fixation. When allelic …