The main mechanism proposed for formation of homologous translocations/
isochromosomes is mitotic and if this occurs in a chromosomally normal conceptus …

We report a patient with a de novo translocation 13/18, identified by high-resolution banding.
The breakpoints were ascertained by fluorescence in situ hybridisation with whole …

We report an unusual case of a familial complex chromosome rearrangement (CCR),
ascertained through prenatal diagnosis. The fetus carried an apparently balanced CCR with …

Objective To investigate the incidence and pregnancy outcome of prenatally diagnosed
balanced chromosome rearrangements from amniocentesis. Study design Between January …

Balanced reciprocal translocation mosaicism is rarely reported in humans. Only two
previous cases have been associated with an abnormal phenotype. We report on a third …

Mosaicism for a balanced reciprocal translocation is uncommon. These two new cases were
detected during investigation of infertility and miscarriages. Otherwise, the probands were …

Background Mosaicism for chromosomal structural rearrangements (Rea) is rare and the
timing and mechanisms of mosaic Rea formation, maintenance, and clinical manifestation …

In a recent issue of your journal, Fryns and Kleczkowska [1986] emphasize, about the report
of Sciorra et al [1986], that mosaic “balanced” reciprocal translocations are rare. They report …

The predominance of females segregating chromosome aberrations to their offspring has
been explained mostly by selection disadvantage of unbalanced products of …

Fifty chromosomally normal couples with three or more miscarriages were examined using
fluorescent in situ hybridisation (FISH) and a library of subtelomere-specific probes together …