Background Perioperative mortality is low for patients undergoing abdominal aortic
aneurysm (AAA) repair, but long-term survival remains poor. Although patients diagnosed …

Statins are thought to reduce vascular inflammation through lipid independent mechanisms.
Evaluation of such an effect in atherosclerotic disease is complicated by simultaneous …

Background Aortic calcification has been shown to share the same risk factors as
atherosclerosis which suggested a potential benefit from statins therapy. In view of the …

Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

Objective Many patients undergoing vascular surgical procedures are not on appropriate
medical therapy. This study sought to examine the variation and impact of antiplatelet (AP) …

BACKGROUND: Statins reduce cardiac morbidity in nonsurgical populations, and may
benefit surgical patients. We sought to examine cardiac outcome in patients who continued …

INTRODUCTION: Antiplatelet agents, 3-hydroxy-3-methylglutaryl coenzyme A reductase
inhibitors (statin drugs), angiotensin converting enzyme (ACE) inhibitors, and β-adrenergic …

OBJECTIVES: Statins have been reported to suppress the progression of abdominal aortic
aneurysm (AAA). However, the effects of statins on inflammatory processes and free radicals …

Background. Recent publications have highlighted the benefits of statins in non-cardiac
occlusive disease but also the failure of vascular surgeons to recognise and treat the risk …

Objectives Currently there is no drug therapy for abdominal aortic aneurysm (AAA) and most
previous investigations have focused on imaging rather than clinical outcomes. The aim of …