Recent evidence suggests that gamete-imprinted genes play a role in embryo and placenta
development and growth. This systematic review aimed to evaluate whether altered …

Considering the widespread use of assisted reproductive techniques (ART), DNA
methylation of specific genes involved in spermatogenesis achieves increasingly clinical …

STUDY QUESTION What is the sperm DNA methylation status of imprinted genes in male
partners from couples experiencing recurrent pregnancy loss (RPL)? SUMMARY ANSWER …

Given the higher risk of developing imprinting disorders in assisted reproductive technology
(ART)-conceived children, we hypothesized that ART may affect DNA methylation of the …

BACKGROUND Increasing numbers of children are being conceived by assisted
reproductive technology (ART). A number of studies have highlighted an altered epigenetic …

STUDY QUESTION Is there a distinct sperm histone-retained epigenetic signature in
unexplained male factor infertility patients resulting in compromised blastocyst …

Disturbingly, the number of patients with oligozoospermia (low sperm count) has been
gradually increasing in industrialized countries. Epigenetic alterations are believed to be …

Background Altered sperm DNA methylation patterns of imprinted genes as well as certain
spermatogenesis-related genes has been proposed as a possible mechanism of male …

OBJECTIVE: To evaluate genome-wide DNA methylation patterns in sperm from men with
abnormal sperm chromatin packaging and patients displaying abnormal embryogenesis …

Purpose: To evaluate the epigenetic risk linked to assisted reproductive technology (ART) at
single-embryo level by analyzing the methylation status of imprinted H19, PEG1, and …