Background Epigenetic polymorphisms are a potential source of human diversity, but their
frequency and relationship to genetic polymorphisms are unclear. DNA methylation, an …

Background Ethnic differences in human DNA methylation have been shown for a number of
CpG sites, but the genome-wide patterns and extent of these differences are largely …

Genomic DNA methylation profiles exhibit substantial variation within the human population,
with important functional implications for gene regulation. So far little is known about the …

DNA methylation patterns are important for establishing cell, tissue, and organism
phenotypes, but little is known about their contribution to natural human variation. To …

Background DNA methylation plays an essential role in the regulation of gene expression.
While its presence near the transcription start site of a gene has been associated with …

Epigenetic marks such as DNA methylation have generated great interest in the study of
human disease. However, studies of DNA methylation have not established population …

Background There is increasing evidence for inter-individual methylation differences at CpG
dinucleotides in the human genome, but the regional extent and function of these …

Most of the studies characterizing DNA methylation patterns have been restricted to
particular genomic loci in a limited number of human samples and pathological conditions …

Background DNA methylation is a major epigenetic modification important for regulating
gene expression and suppressing spurious transcription. Most methods to scan the genome …

Background DNA methylation, which mainly occurs at CpG dinucleotides, is a dynamic
epigenetic regulation mechanism in most eukaryotic genomes. It is already known that …