Epigenetics can be defined as the study of heritable changes in gene expression without
alteration of the DNA sequence itself. This means that epigenetic variants are stable …

It is my great pleasure to introduce the third edition of DNA Methylation: Methods and
Protocols to the scientific and medical community. DNA methylation at cytosines forms one …

Cytosine methylation is a com-mon DNA modification found in most eukaryotic organisms
including plants, animals, and fungi (1, 2). The addition of a methyl group to cytosine …

DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

DNA methylation and epigenomics: new technologies and emerging concepts | Genome
Biology Skip to main content SpringerLink Account Menu Find a journal Publish with us Track …

Ever since methylcytosine was found in genomic DNA, this epigenetic alteration has
become a center of scientific attraction, especially because of its relation to gene silencing in …

Methylation of cytosines can mediate epigenetic gene silencing and is the only known DNA
modification in eukaryotes. Recent efforts to map DNA methylation across mammalian …

One of the most critical epigenetic signatures present in the genome of higher eukaryotes is
the methylation of DNA at the C-5 position of the cytosine ring. Based on the sites of DNA …

DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …

DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …