Background: Angiotensin II is produced primarily by angiotensin I-converting enzyme (ACE)
within atherosclerotic lesions and ACE level in plaques correlates with the severity of vessel …

Vogt S, Sigusch HH, Gruber U, Reinhardt D, Lang K, Surber R, Farker K, Müller S, Hoffmann
A. Angiotensin-I-converting enzyme DD genotype is a risk factor of coronary heart disease …

Background Coronary artery disease (CAD) is a polygenic disease whose phenotypic
manifestation is due to interaction of a number of environmental factors with an underlying …

Background Although both genetic and nongenetic factors contribute to the pathogenesis of
coronary artery disease, the identification of specific genetic lesions has lagged behind the …

Background An insertion/deletion (I/D) polymorphism of the angiotensin I–converting
enzyme (ACE) gene has been postulated to be associated with an increased risk of …

Objectives We investigated the association between insertion/deletion polymorphism of the
angiotensin I-converting enzyme (ACE) gene, the presence and extent of coronary artery …

Background Mutations in genes regulating lipid metabolism, vasoactivity, and coagulation
are important modulators of coronary artery disease (CAD). Objective This study …

Background The deletion (D) allele of the angiotensin‐converting enzyme (ACE) gene has
been proposed as a genetic marker of the risk of ischaemic heart disease. However, the …

We investigated whether the insertion/deletion (I/D) polymorphism in the angiotensin-
converting enzyme (ACE) gene and serum ACE levels are associated with traditional risk …

OBJECTIVE: The role of angiotensin converting enzyme (ACE) gene insertion/deletion (I/D)
polymorphism in early onset coronary artery disease age< 55years (ECAD) is controversial …