Rationale: Prenatal exposure to tobacco smoke increases the risk for diseases later in the
child's life that may be mediated through alterations in DNA methylation. Objectives: To …

Background Smoking while pregnant is associated with a myriad of negative health
outcomes in the child. Some of the detrimental effects may be due to epigenetic …

Background Prenatal smoke exposure is known to be robustly associated with DNA
methylation among offspring in early life, but whether the association persists into adulthood …

Prenatal exposure to tobacco smoke has lifelong health consequences. Epigenetic
signatures such as differences in DNA methylation (DNAm) may be a biomarker of exposure …

Background: Prenatal exposure to maternal cigarette smoking (prenatal smoke exposure)
had been associated with altered DNA methylation (DNAm) at birth. Objective: We examined …

In utero smoke exposure has been shown to have detrimental effects on lung function and to
be associated with persistent wheezing and asthma in children. One potential mechanism of …

Aim: Cigarette smoking influences DNA methylation genome wide, in newborns from
pregnancy exposure and in adults from personal smoking. Whether a unique methylation …

Background: Maternal smoking during pregnancy is associated with significant infant
morbidity and mortality, and may influence later disease risk. One mechanism by which …

Maternal smoking during pregnancy has been found to influence newborn DNA methylation
in genes involved in fundamental developmental processes. It is pertinent to understand the …

Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures
may play a critical role in early programming for childhood and adult illness. Maternal …