A better understanding of carbon dioxide (CO2) effect on brain activity may have a profound
impact on clinical studies using CO2 manipulation to assess cerebrovascular reserve and …

The effect of carbon dioxide (CO2) on cerebral metabolism is of tremendous interest to
functional imaging. In particular, mild-to-moderate hypercapnia is routinely used in …

Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI)
is most commonly used in a semi-quantitative manner to infer changes in brain activity …

Hypercapnia is often used as vasodilatory challenge in clinical applications and basic
research. In functional magnetic resonance imaging (fMRI), elevated CO2 is applied to …

The calibration of functional magnetic resonance imaging (fMRI) for the estimation of
neuronal activation-induced changes in cerebral metabolic rate of oxygen (CMRO2) has …

The effect of hypercapnia on cerebral metabolic rate of oxygen consumption (CMRO 2) has
been a subject of intensive investigation and debate. Most applications of hypercapnia are …

Investigations into the blood oxygenation level-dependent (BOLD) functional MRI signal
have used respiratory challenges with the aim of probing cerebrovascular physiology. Such …

Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …

The aim was to investigate the effect of different speech tasks, ie recitation of prose (PR),
alliteration (AR) and hexameter (HR) verses and a control task (mental arithmetic (MA) with …

Carbon monoxide (CO) may inhibit mitochondrial electron transport in the brain and
increase the toxic effects of the gas. This hypothesis was investigated in anesthetized rats …