Active DNA demethylation and DNA repair

C Niehrs - Differentiation, 2009 - Elsevier
DNA methylation on cytosine is an epigenetic modification and is essential for gene
regulation and genome stability in vertebrates. Traditionally DNA methylation was …

[HTML][HTML] Active DNA demethylation by oxidation and repair

Z Gong, JK Zhu - Cell research, 2011 - nature.com
DNA methylation and demethylation are increasingly recognized as important epigenetic
factors in both plants and animals. DNA methylation, which is catalyzed by DNA …

Active DNA demethylation by DNA repair: Facts and uncertainties

D Schuermann, AR Weber, P Schär - DNA repair, 2016 - Elsevier
Pathways that control and modulate DNA methylation patterning in mammalian cells were
poorly understood for a long time, although their importance in establishing and maintaining …

DNA demethylation by TDG

SR Dalton, A Bellacosa - Epigenomics, 2012 - Taylor & Francis
DNA methylation has long been considered a very stable DNA modification in mammals that
could only be removed by replication in the absence of remethylation–that is, by mere …

DNA methylation in eukaryotes

RA Martienssen, EJ Richards - Current opinion in genetics & development, 1995 - Elsevier
Recent advances have expanded our understanding of the processes underlying the
establishment, maintenance, and elaboration of DNA methylation patterns in eukaryotes …

DNA methylation dynamics in plants and mammals: overview of regulation and dysregulation

AR Elhamamsy - Cell biochemistry and function, 2016 - Wiley Online Library
DNA methylation is a major epigenetic marking mechanism regulating various biological
functions in mammals and plant. The crucial role of DNA methylation has been observed in …

New insights into mechanisms that regulate DNA methylation patterning

G Ficz - Journal of Experimental Biology, 2015 - journals.biologists.com
From a fertilised egg to a mature organism, cells divide and accumulate epigenetic
information, which is faithfully passed on to daughter cells. DNA methylation consolidates …

[HTML][HTML] Regulation and function of DNA methylation in plants and animals

XJ He, T Chen, JK Zhu - Cell research, 2011 - nature.com
DNA methylation is an important epigenetic mark involved in diverse biological processes.
In plants, DNA methylation can be established through the RNA-directed DNA methylation …

Active DNA demethylation: many roads lead to Rome

SC Wu, Y Zhang - Nature reviews Molecular cell biology, 2010 - nature.com
DNA methylation is one of the best-characterized epigenetic modifications and has been
implicated in numerous biological processes, including transposable element silencing …

[HTML][HTML] DNA methylation and demethylation in mammals

Z Chen, AD Riggs - Journal of Biological Chemistry, 2011 - ASBMB
Cell type-specific DNA methylation patterns are established during mammalian
development and maintained in adult somatic cells. Understanding how these patterns of 5 …