Extensive epigenetic reprogramming occurs during mammalian gametogenesis and
preimplantation development. DNA methylation patterns that are laid down during these …

DNA methylation is an important epigenetic modification that undergoes dynamic changes
in mammalian embryogenesis, during which both parental genomes are reprogrammed …

BACKGROUND Although assisted reproductive technology (ART) is reported to result in
abnormal genomic imprinting and/or altered genomic methylation, few if any studies have …

With boundaries in epigenetic mapping methods and technologies being constantly pushed
further, major advances in our understanding of these regulatory mechanisms are being …

For developmental competence of mammalian embryos, dynamic epigenetic changes to
both the maternally and paternally derived contributions to the genome of the zygote should …

DNA methylation is a crucial layer of epigenetic regulation during mammalian embryonic
development,–. Although the DNA methylome of early human embryos has been analyzed …

Recently, differences in DNA methylation patterns in placental and umbilical blood samples
taken from children born after IVF and children conceived naturally have been reported …

Active demethylation of the paternal genome but not of the maternal genome occurs in
fertilized mouse, rat, pig, and bovine zygotes. To study whether this early demethylation …

Early embryonic development in the pig requires DNA methylation remodeling of the
maternal and paternal genomes. Aberrant remodeling, which can be exasperated by in vitro …

Background In their attempt to fulfill the wish of having children, women who suffer from
fertility issues often undergo assisted reproductive technologies such as ovarian stimulation …