Oxygen‐sensitive MRI assessment of tumor response to hypoxic gas breathing challenge
Oxygen‐sensitive MRI has been extensively used to investigate tumor oxygenation based
on the response (R2* and/or R1) to a gas breathing challenge. Most studies have reported …
on the response (R2* and/or R1) to a gas breathing challenge. Most studies have reported …
Dynamic oxygen challenge evaluated by NMR T1 and T2* – insights into tumor oxygenation
D Zhao, J Pacheco‐Torres, RR Hallac… - NMR in …, 2015 - Wiley Online Library
There is intense interest in developing non‐invasive prognostic biomarkers of tumor
response to therapy, particularly with regard to hypoxia. It has been suggested that oxygen …
response to therapy, particularly with regard to hypoxia. It has been suggested that oxygen …
Combined endogenous MR biomarkers to predict basal tumor oxygenation and response to hyperoxic challenge
Hypoxia is a common feature of solid tumors, which translates into increased angiogenesis,
malignant phenotype cell selection, change in gene expression and greater resistance to …
malignant phenotype cell selection, change in gene expression and greater resistance to …
Comparison of 1H blood oxygen level–dependent (BOLD) and 19F MRI to investigate tumor oxygenation
D Zhao, L Jiang, EW Hahn… - Magnetic Resonance in …, 2009 - Wiley Online Library
Abstract Fluorine‐19 [19F] MRI oximetry and 1H blood oxygen level–dependent (BOLD) MRI
were used to investigate tumor oxygenation in rat breast 13762NF carcinomas, and …
were used to investigate tumor oxygenation in rat breast 13762NF carcinomas, and …
Oxygen-sensitive MRI: a predictive imaging biomarker for tumor radiation response?
Purpose To develop a noninvasive prognostic imaging biomarker related to hypoxia to
predict SABR tumor control. Methods and Materials A total of 145 subcutaneous syngeneic …
predict SABR tumor control. Methods and Materials A total of 145 subcutaneous syngeneic …
Correlations of noninvasive BOLD and TOLD MRI with pO2 and relevance to tumor radiation response
Purpose To examine the potential use of blood oxygenation level dependent (BOLD) and
tissue oxygenation level dependent (TOLD) contrast MRI to assess tumor oxygenation and …
tissue oxygenation level dependent (TOLD) contrast MRI to assess tumor oxygenation and …
Quantitative MRI assessment of VX2 tumour oxygenation changes in response to hyperoxia and hypercapnia
Magnetic resonance imaging (MRI) relaxation times provide indirect estimates of tissue O 2
for monitoring tumour oxygenation. This study provides insight into mechanisms underlying …
for monitoring tumour oxygenation. This study provides insight into mechanisms underlying …
How does blood oxygen level‐dependent (BOLD) contrast correlate with oxygen partial pressure (pO2) inside tumors?
C Baudelet, B Gallez - … in Medicine: An Official Journal of the …, 2002 - Wiley Online Library
Blood oxygen level‐dependent (BOLD) contrast‐based functional MRI (fMRI) has been
reported as a method to assess the evolution of tumor oxygenation after hyperoxic …
reported as a method to assess the evolution of tumor oxygenation after hyperoxic …
Current issues in the utility of blood oxygen level dependent MRI for the assessment of modulations in tumor oxygenation
C Baudelet, B Gallez - Current Medical Imaging, 2005 - ingentaconnect.com
It has been known for some time now that hypoxia is an important physiological parameter in
tumor growth and response to therapy. The development and application of non invasive …
tumor growth and response to therapy. The development and application of non invasive …
Fast and sensitive dynamic oxygen‐enhanced MRI with a cycling gas challenge and independent component analysis
Purpose There is a critical need for non‐invasive imaging biomarkers of tumor oxygenation
to assist in patient stratification and development of hypoxia targeting therapies. Using a …
to assist in patient stratification and development of hypoxia targeting therapies. Using a …