MethBank: a database integrating next-generation sequencing single-base-resolution DNA methylation programming data

D Zou, S Sun, R Li, J Liu, J Zhang… - Nucleic acids …, 2015 - academic.oup.com
DNA methylation plays crucial roles during embryonic development. Here we present
MethBank (http://dnamethylome. org), a DNA methylome programming database that …

MethBank 4.0: an updated database of DNA methylation across a variety of species

M Zhang, W Zong, D Zou, G Wang, W Zhao… - Nucleic Acids …, 2023 - academic.oup.com
DNA methylation, as the most intensively studied epigenetic mark, regulates gene
expression in numerous biological processes including development, aging, and disease …

MethBank 3.0: a database of DNA methylomes across a variety of species

R Li, F Liang, M Li, D Zou, S Sun, Y Zhao… - Nucleic acids …, 2018 - academic.oup.com
Abstract MethBank (http://bigd. big. ac. cn/methbank) is a database that integrates high-
quality DNA methylomes across a variety of species and provides an interactive browser for …

DNA methylation reprogramming of functional elements during mammalian embryonic development

C Li, Y Fan, G Li, X Xu, J Duan, R Li, X Kang, X Ma… - Cell discovery, 2018 - nature.com
DNA methylation plays important roles during development. However, the DNA methylation
reprogramming of functional elements has not been fully investigated during mammalian …

Embryonic DNA methylation: insights from the genomics era

O Bogdanović… - Briefings in functional …, 2014 - academic.oup.com
DNA methylation is an epigenetic mark associated with transcriptional repression and
essential for proper vertebrate development. Because of its association with human …

Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes

Z Su, L Han, Z Zhao - Epigenetics, 2011 - Taylor & Francis
DNA methylation is one of the most important heritable epigenetic modifications of the
genome and is involved in the regulation of many cellular processes. Aberrant DNA …

Evolutionary conservation of embryonic DNA methylome remodelling in distantly related teleost species

SE Ross, J Vázquez-Marín, KRB Gert… - Nucleic Acids …, 2023 - academic.oup.com
Methylation of cytosines in the CG context (mCG) is the most abundant DNA modification in
vertebrates that plays crucial roles in cellular differentiation and identity. After fertilization …

Genome‐wide DNA methylation profiling

M Bibikova, JB Fan - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos

HJ Lee, RF Lowdon, B Maricque, B Zhang… - Nature …, 2015 - nature.com
DNA methylation undergoes dynamic changes during development and cell differentiation.
Recent genome-wide studies discovered that tissue-specific differentially methylated …

NGSmethDB: a database for next-generation sequencing single-cytosine-resolution DNA methylation data

M Hackenberg, G Barturen, JL Oliver - Nucleic acids research, 2010 - academic.oup.com
Next-generation sequencing (NGS) together with bisulphite conversion allows the
generation of whole genome methylation maps at single-cytosine resolution. This allows …