Methylation at CpG dinucleotides is important for gene regulation in mammals [1]. However,
it is unknown how methylation patterns change during evolution. Here, we compare …

Abstract We applied Illumina Human Methylation450K array to perform a genomic-scale
single-site resolution DNA methylation analysis in neuronal and nonneuronal (primarily …

Epigenetic mechanisms, including DNA methylation, that underlie neuropsychiatric
conditions have become a promising area of research. Most commonly used DNA sources …

DNA methylation in the germline is among the most important factors influencing the
evolution of mammalian genomes. Yet little is known about its evolutionary rate or the …

As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types …

Introduction Several lines of evidence point to a key role for dynamic epigenetic changes
during brain development, maturation, and learning. DNA methylation (mC) is a stable …

Abstract MethylomeDB (http://epigenomics. columbia. edu/methylomedb/index. html) is a
new database containing genome-wide brain DNA methylation profiles. DNA methylation is …

DNA methylation has been traditionally viewed as a highly stable epigenetic mark in
postmitotic cells. However, postnatal brains appear to show stimulus-induced methylation …

DNA methylation is a heritable modification of genomic DNA central to development,
imprinting, transcriptional regulation, chromatin structure, and overall genomic stability …

A fundamental challenge in the post-genome era is to understand and annotate the
consequences of genetic variation, particularly within the context of human tissues. We …