Parent-of-origin DNA methylation dynamics during mouse development
Y Stelzer, H Wu, Y Song, CS Shivalila, S Markoulaki… - Cell reports, 2016 - cell.com
Parent-specific differentially methylated regions (DMRs) are established during
gametogenesis and regulate parent-specific expression of imprinted genes. Monoallelic …
gametogenesis and regulate parent-specific expression of imprinted genes. Monoallelic …
The human blood DNA methylome displays a highly distinctive profile compared with other somatic tissues
R Lowe, G Slodkowicz, N Goldman, VK Rakyan - Epigenetics, 2015 - Taylor & Francis
In mammals, DNA methylation profiles vary substantially between tissues. Recent genome-
scale studies report that blood displays a highly distinctive methylomic profile from other …
scale studies report that blood displays a highly distinctive methylomic profile from other …
Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation
Background DNA methylation (DNAm) is a critical regulator of both development and
cellular identity and shows unique patterns in neurons. To better characterize maturational …
cellular identity and shows unique patterns in neurons. To better characterize maturational …
Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type
Background Individual genotypes at specific loci can result in different patterns of DNA
methylation. These methylation quantitative trait loci (meQTLs) influence methylation across …
methylation. These methylation quantitative trait loci (meQTLs) influence methylation across …
Systematic DNA methylation analysis of multiple cell lines reveals common and specific patterns within and across tissues of origin
DNA methylation is a key functional regulatory mechanism in human genome, which plays
critical roles in development, differentiation and many diseases. With rapid progress of large …
critical roles in development, differentiation and many diseases. With rapid progress of large …
A survey of inter-individual variation in DNA methylation identifies environmentally responsive co-regulated networks of epigenetic variation in the human genome
While population studies have resulted in detailed maps of genetic variation in humans, to
date there are few robust maps of epigenetic variation. We identified sites containing …
date there are few robust maps of epigenetic variation. We identified sites containing …
Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences
E Schilling, C El Chartouni, M Rehli - Genome research, 2009 - genome.cshlp.org
DNA methylation is a vital epigenetic mark that participates in establishing and maintaining
chromatin structures and regulates gene transcription during mammalian development and …
chromatin structures and regulates gene transcription during mammalian development and …
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
Background DNA methylation is an essential epigenetic mechanism involved in gene
regulation and disease, but little is known about the mechanisms underlying inter-individual …
regulation and disease, but little is known about the mechanisms underlying inter-individual …
Methods in DNA methylation profiling
Metastable and somatically heritable patterns of DNA methylation provide an important level
of genomic regulation. In this article, we review methods for analyzing these genome-wide …
of genomic regulation. In this article, we review methods for analyzing these genome-wide …
Mapping of variable DNA methylation across multiple cell types defines a dynamic regulatory landscape of the human genome
DNA methylation is an important epigenetic modification involved in many biological
processes and diseases. Many studies have mapped DNA methylation changes associated …
processes and diseases. Many studies have mapped DNA methylation changes associated …