Roles of confined placental mosaicism (CPM) and H19/IGF2 imprinting in pregnancies derived from intracytoplasmic sperm injection (ICSI)

C Hatakeyama - 2007 - open.library.ubc.ca
In contrast to the success of ICSI in treating male infertility, concerns have been raised about
the health outcomes of the children conceived through this procedure. Cohort studies have …

Investigation of confined placental mosaicism (CPM) at multiple sites in post‐delivery placentas derived through intracytoplasmic sperm injection (ICSI)

A Minor, K Harmer, N Peters… - American Journal of …, 2006 - Wiley Online Library
Although earlier studies on pregnancies derived through intracytoplasmic sperm injection
(ICSI) reported increased non‐mosaic aneuploidy among ICSI children, undetected …

Investigation of confined placental mosaicism by CGH in IVF and ICSI pregnancies

EC Wong, C Hatakeyama, A Minor, S Ma - Placenta, 2012 - Elsevier
BACKGROUND: Assisted reproductive technologies include in-vitro fertilization (IVF) and
intracytoplasmic sperm injection (ICSI). It has been shown that embryos derived from ART …

Altered gene expression of H19 and IGF2 in placentas from ART pregnancies

S Sakian, K Louie, EC Wong, J Havelock, S Kashyap… - Placenta, 2015 - Elsevier
Introduction The aim of this study is to determine whether the gene expression and
associated DNA methylation regulation of H19 and IGF2 are altered in placentas conceived …

Does confined placental mosaicism account for adverse perinatal outcomes in IVF pregnancies?

BC Jacod, KD Lichtenbelt… - Human …, 2008 - academic.oup.com
BACKGROUND IVF singletons have poorer perinatal outcomes than singletons from
spontaneous conceptions. This may be due to the influence of ovarian stimulation on the …

Rare chromosomal, genetic, and epigenetic-related risks associated with infertility treatment

JJ Kurinczuk, S Bhattacharya - Seminars in Fetal and Neonatal Medicine, 2014 - Elsevier
This article reviews the rarer chromosomal, genetic, and epigenetic-related risks of adverse
child outcomes associated with infertility and its treatment. Excess structural chromosomal …

Placental imprinting variation associated with assisted reproductive technologies and subfertility

JF Litzky, MA Deyssenroth, TM Everson… - Epigenetics, 2017 - Taylor & Francis
Infertility affects one in 6 couples in developed nations, resulting in an increasing use of
assisted reproductive technologies (ART). Both ART and subfertility appear to be linked to …

Intracytoplasmic sperm injection: current perspectives and future development

AC Varghese, A Arsalan, A Agarwal - Archives of Medical Science …, 2009 - termedia.pl
Intracytoplasmic sperm injection (ICSI), a novel technique rapidly gaining popularity among
infertile couples, alleviates the burdens posed by male factor infertility by offering infertile …

[PDF][PDF] Research Letter X-Chromosome Inactivation and Telomere Size in Newborns Resulting From Intracytoplasmic Sperm Injection

WP Robinson, MS Penaherrera, J Gair… - American journal of …, 2005 - academia.edu
In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are generally
considered to be safe technologies for treatment of infertility. However, there is evidence …

Placentas from pregnancies conceived by IVF/ICSI have a reduced DNA methylation level at the H19 and MEST differentially methylated regions

ECM Nelissen, JCM Dumoulin, A Daunay… - Human …, 2013 - academic.oup.com
Abstract STUDY QUESTION Does IVF/ICSI have an effect on the epigenetic regulation of the
human placenta? SUMMARY ANSWER We found a reduced DNA methylation level at the …