Functional brain imaging using a blood oxygenation sensitive steady state

KL Miller, BA Hargreaves, J Lee, D Ress… - … in Medicine: An …, 2003 - Wiley Online Library
Blood oxygenation level dependent (BOLD) functional MRI (fMRI) is an important method for
functional neuroimaging that is sensitive to changes in blood oxygenation related to brain …

Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2

L Huber, K Uludağ, HE Möller - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

Characterization of regional heterogeneity in cerebrovascular reactivity dynamics using novel hypocapnia task and BOLD fMRI

MG Bright, DP Bulte, P Jezzard, JH Duyn - Neuroimage, 2009 - Elsevier
We offer a new method for characterizing the magnitude and dynamics of the vascular
response to changes in arterial gas tensions using non-invasive blood oxygenation level …

Cerebral blood flow response to acute hypoxic hypoxia

AD Harris, K Murphy, CM Diaz, N Saxena… - NMR in …, 2013 - Wiley Online Library
Hypoxic hypoxia (inspiratory hypoxia) stimulates an increase in cerebral blood flow (CBF)
maintaining oxygen delivery to the brain. However, this response, particularly at the tissue …

Assessment of cerebral oxidative metabolism with breath holding and fMRI

A Kastrup, G Krüger, GH Glover… - Magnetic Resonance in …, 1999 - Wiley Online Library
Carbon dioxide inhalation can be used to map changes in cerebral metabolic rate of oxygen
(CMRo2) during neuronal activation with functional MRI (fMRI). A hypercapnic stress also …

Time delay processing of hypercapnic fMRI allows quantitative parameterization of cerebrovascular reactivity and blood flow delays

MJ Donahue, MK Strother, KP Lindsey… - Journal of Cerebral …, 2016 - journals.sagepub.com
Blood oxygenation level-dependent fMRI contrast depends on the volume and oxygenation
of blood flowing through the circulatory system. The effects on image intensity depend …

New insights into central roles of cerebral oxygen metabolism in the resting and stimulus-evoked brain

XH Zhu, N Zhang, Y Zhang… - Journal of Cerebral …, 2009 - journals.sagepub.com
The possible role of oxygen metabolism in supporting brain activation remains elusive. We
have used a newly developed neuroimaging approach based on high-field in vivo 17O …

Mapping of the cerebral vascular response to hypoxia and hypercapnia using quantitative perfusion MRI at 3 T

U Nöth, F Kotajima, R Deichmann, R Turner… - NMR in …, 2008 - Wiley Online Library
Abstract Changes in breathing change the concentration of oxygen and carbon dioxide in
arterial blood resulting in changes in cerebral blood flow (CBF). This mechanism can be …

Simultaneous MRI acquisition of blood volume, blood flow, and blood oxygenation information during brain activation

Y Yang, H Gu, EA Stein - … in Medicine: An Official Journal of the …, 2004 - Wiley Online Library
Simultaneous acquisition of complementary functional hemodynamic indices reflecting
different aspects of brain activity would be a valuable tool for functional brain‐imaging …

[HTML][HTML] The absolute CBF response to activation is preserved during elevated perfusion: Implications for neurovascular coupling measures

JR Whittaker, ID Driver, MG Bright, K Murphy - Neuroimage, 2016 - Elsevier
Functional magnetic resonance imaging (fMRI) techniques in which the blood oxygenation
level dependent (BOLD) and cerebral blood flow (CBF) response to a neural stimulus are …