Functional magnetic resonance imaging (fMRI) techniques in which the blood oxygenation
level dependent (BOLD) and cerebral blood flow (CBF) response to a neural stimulus are …

We offer a new method for characterizing the magnitude and dynamics of the vascular
response to changes in arterial gas tensions using non-invasive blood oxygenation level …

Background and Purpose—A noninvasive MRI method to measure cerebral oxygen
metabolism has the potential to assess tissue viability during cerebral ischemia. The …

The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

The calibrated BOLD (blood oxygen level dependent) technique was developed to quantify
the BOLD signal in terms of changes in oxygen metabolism. In order to achieve this a …

Purpose To map the cerebral metabolic rate of oxygen (CMRO2) by estimating the oxygen
extraction fraction (OEF) from gradient echo imaging (GRE) using phase and magnitude of …

Since Ogawa et al.(Proc Natl Acad Sci USA 1990; 87: 9868–9872) made the fundamental
discovery of blood oxygenation leveldependent (BOLD) contrast in MRI, most efforts have …

A quantitative estimate of cerebral blood oxygen saturation is of critical importance in the
investigation of cerebrovascular disease. While positron emission tomography can map in …

Cerebrovascular reactivity (CVR) reflects the capacity of blood vessels to dilate and is an
important marker for brain vascular reserve. It may provide a useful addition to the traditional …

Purpose To assess the effect of changes in end‐tidal partial pressure of O2 (PetO2) on
cerebrovascular reactivity (CVR) estimated from changes in blood oxygen level–dependent …