There is increasing appreciation that changes in microbiome composition and function can
promote long-term susceptibility for cardiometabolic risk. Gut microbe-derived metabolites …

Morbidity and mortality of cardiovascular diseases (CVDs) are exceedingly high worldwide.
Researchers have found that the occurrence and development of CVDs are closely related …

The extensive collection of bacteria cohabiting within the host collaborates with human
functions and metabolisms in both health and disease. The fine equilibrium of commensals …

Cardiometabolic diseases (CMDs) have been associated with changes in the composition of
the gut microbiota, with links between the host environment and microbiota identified in …

Context Several studies suggest a relationship between trimethylamine N-oxide (TMAO)
concentrations and increased cardiometabolic risk, but findings are controversial. Objective …

We critically review potential involvement of trimethylamine N-oxide (TMAO) as a link
between diet, the gut microbiota and CVD. Generated primarily from dietary choline and …

Trimethylamine N-oxide (TMAO) is a circulating metabolite that has been implicated in the
development of atherosclerosis and cardiovascular disease (CVD). In this paper, we identify …

Trimethylamine-N-oxide (TMAO) is the main diet-induced metabolite produced by the gut
microbiota, and it is mainly eliminated through renal excretion. TMAO has been correlated …

ABSTRACT Background Trimethylamine-N-oxide (TMAO), a diet-derived and gut microbiota–
related metabolite, is associated with cardiovascular disease (CVD). However, major dietary …

Traditional cardiovascular risk factors do not underlie all incidence of cardiovascular
disease. In recent years, accumulating evidence has demonstrated that gut microbiota and …