Although stromal cells establish the architecture of mammalian bone marrow and organize
hemopoiesis, the interrelationships among their macrophage, fibroblastic, endothelial, and …

Background: The involvement of bone marrow (BM) in tumor‐stroma reactions or tumor
development has not been examined in a cancer allograft, which has otherwise been …

マウス口腔扁平上皮癌細胞 Sq-1079 は, IL-1α を放出し, 間葉系細胞 10T1/2 が,
脾細胞との細胞接触により発揮する免疫抑制作用を有意に増強することが判明した.

Background: High concentrations of interferon beta (IFN-β) inhibit malignant cell growth in
vitro. However, the therapeutic utility of IFN-β in vivo is limited by its excessive toxicity when …

We have developed and characterized a murine mesenchymal stem cell line from the bone
marrow of transgenic mouse C57BL ubiquitously expressing GFP. Immunostaining analysis …

Two transformed stromal cell lines FM-7 and FR-7 were obtained from human xenografts of
colon tumor (HCT-7), propagated in nude mice and nude rats, respectively. These two cell …

Mesenchymal stromal cells (MSCs), also called mesenchymal stem cells, migrate and
function as stromal cells in tumor tissues. The effects of MSCs on tumor growth are …

マウス口腔扁平上皮癌細胞 Sq-1079 は, IL-1α を放出し, 間葉系細胞 10T1/2 が,
脾細胞との細胞接触により発揮する免疫抑制作用を有意に増強することが判明した.

T-cell lymphoblastic leukemia (T-ALL) is a hematological hematopoietic T cell precursor
disorder with a not well defined etiology, although it would be linked to NOTCH signaling …

The presence of tumor‐infiltrating lymphocytes (TIL) provides important evidence of anti‐
tumor immunity in vivo. However, TIL are usually not sufficient for inhibiting tumor growth …