Differentiation-related DNA methylation is receiving increasing attention, partly owing to
new, whole-genome analyses. These revealed that cell type-specific differential methylation …

One of the most critical epigenetic signatures present in the genome of higher eukaryotes is
the methylation of DNA at the C-5 position of the cytosine ring. Based on the sites of DNA …

DNA methylation is a critical epigenetic regulator in mammalian development. Here, we
present a whole-genome comparative view of DNA methylation using bisulfite sequencing of …

It has been nearly 40 y since it was suggested that genomic methylation patterns could be
transmitted via maintenance methylation during S phase and might play a role in the …

Myogenic cell cultures derived from muscle biopsies are excellent models for human cell
differentiation. We report the first comprehensive analysis of myogenesis-specific DNA hyper …

Methylation of cytosines can mediate epigenetic gene silencing and is the only known DNA
modification in eukaryotes. Recent efforts to map DNA methylation across mammalian …

DNA methylation is an essential epigenetic modification for mammalian development and is
crucial for the establishment and maintenance of cellular identity. Traditionally, DNA …

Background Uncovering mechanisms of epigenome evolution is an essential step towards
understanding the evolution of different cellular phenotypes. While studies have confirmed …

DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …

Over three decades ago DNA methylation had been suggested to play a role in the
regulation of gene expression. This chapter reviews the development of this field of research …