Abstract Changes in DNA methylation have been found in the large majority of tumors. This
phenomenon includes both genome‐wide hypomethylation and gene‐specific …

Purpose Since its discovery 50 years ago, DNA methylation has been found to be an
important part of gene regulation. Newer methods of analysis over the last decade have …

DNA methylation contributes to the control of gene expression and plays an essential role in
cellular physiology. Well-defined patterns of DNA methylation are established and fixed …

The amnion is a specialized tissue in contact with the amniotic fluid, which is in a constantly
changing state. To investigate the importance of epigenetic events in this tissue in the …

Background The association of in vitro fertilisation (IVF) and DNA methylation has been
studied predominantly at regulatory regions of imprinted genes and at just thousands of the …

Background Several independent research groups have shown that alterations in human
sperm methylation profiles correlate with decreased fecundity and an increased risk of poor …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

There is increasing interest in understanding the potential for epigenetic factors to contribute
to phenotypic diversity in evolutionary biology. One well studied epigenetic mechanism is …

Cell therapeutic approaches currently lack definitive quality control measures which
guarantee safety in clinical applications and create consistent standards for regulatory …

Epigenetic processes, such as DNA methylation, are known to regulate tissue specific gene
expression. We explored this concept in the placenta to define whether DNA methylation is …