Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation …
Accepted: 4 May 2013/Published online: 14 May 2013© The Author (s) 2013. This article is
published with open access at Springerlink. com are becoming increasingly important, not …
published with open access at Springerlink. com are becoming increasingly important, not …
High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array
H Hayashi, G Nagae, S Tsutsumi, K Kaneshiro… - Human genetics, 2007 - Springer
DNA methylation is an epigenetic mark crucial in regulation of gene expression. Aberrant
DNA methylation causes silencing of tumor suppressor genes and promotes chromosomal …
DNA methylation causes silencing of tumor suppressor genes and promotes chromosomal …
Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of …
HA Rogers, JP Kilday, C Mayne, J Ward… - Acta …, 2012 - Springer
Epigenetic alterations, including methylation, have been shown to be an important
mechanism of gene silencing in cancer. Ependymoma has been well characterized at the …
mechanism of gene silencing in cancer. Ependymoma has been well characterized at the …
MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma
Z Zhang, H Tang, Z Wang, B Zhang, W Liu, H Lu… - Molecular cancer, 2011 - Springer
Background Perturbation of DNA methylation is frequent in cancers and has emerged as an
important mechanism involved in tumorigenesis. To determine how DNA methylation is …
important mechanism involved in tumorigenesis. To determine how DNA methylation is …
Methylation-specific oligonucleotide microarray
PS Yan, SH Wei, THM Huang - Epigenetics Protocols, 2004 - Springer
The methylation-specific oligonucleotide (MSO) microarray is a high-throughput approach
capable of detecting DNA methylation in genes across several CpG sites. Based on the …
capable of detecting DNA methylation in genes across several CpG sites. Based on the …
Genome-wide methylation analyses in glioblastoma multiforme
Few studies had investigated genome-wide methylation in glioblastoma multiforme (GBM).
Our goals were to study differential methylation across the genome in gene promoters using …
Our goals were to study differential methylation across the genome in gene promoters using …
Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis
Oligonucleotide microarray-based hybridization is an emerging technology for genome-wide
detection of DNA variations. We have extended this principle and developed a novel …
detection of DNA variations. We have extended this principle and developed a novel …
A qPCR technology for direct quantification of methylation in untreated DNA
KK Bendixen, M Mindegaard, S Epistolio… - Nature …, 2023 - nature.com
DNA methylation is important for gene expression and alterations in DNA methylation are
involved in the development and progression of cancer and other major diseases. Analysis …
involved in the development and progression of cancer and other major diseases. Analysis …
Methylation analysis by DNA immunoprecipitation (MeDIP)
Alteration in epigenetic regulation of gene expression is a common event in human cancer
and developmental disease. CpG island hypermethylation and consequent gene silencing …
and developmental disease. CpG island hypermethylation and consequent gene silencing …
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma
J Hoebeeck, E Michels, F Pattyn, V Combaret… - Cancer letters, 2009 - Elsevier
CpG island hypermethylation has been recognized as an alternative mechanism for tumor
suppressor gene inactivation. In this study, we performed methylation-specific PCR (MSP) to …
suppressor gene inactivation. In this study, we performed methylation-specific PCR (MSP) to …