[HTML][HTML] A data-driven approach to preprocessing Illumina 450K methylation array data
Background As the most stable and experimentally accessible epigenetic mark, DNA
methylation is of great interest to the research community. The landscape of DNA …
methylation is of great interest to the research community. The landscape of DNA …
Evidence for an instructive mechanism of de novo methylation in cancer cells
I Keshet, Y Schlesinger, S Farkash, E Rand, M Hecht… - Nature …, 2006 - nature.com
DNA methylation has a role in the regulation of gene expression during normal mammalian
development but can also mediate epigenetic silencing of CpG island genes in cancer and …
development but can also mediate epigenetic silencing of CpG island genes in cancer and …
[PDF][PDF] DNA methylation in brain development and gliomagenesis
JF Costello - Front Biosci, 2003 - article.imrpress.com
[Frontiers in Bioscience 8, s175-184, January 1, 2003] DNA METHYLATION IN BRAIN
DEVELOPMENT AND GLIOMAGENESIS Joseph F. Costello Page 1 [Frontiers in …
DEVELOPMENT AND GLIOMAGENESIS Joseph F. Costello Page 1 [Frontiers in …
Copy number variation has little impact on bead-array-based measures of DNA methylation
EA Houseman, BC Christensen, MR Karagas… - …, 2009 - academic.oup.com
Motivation: Integration of various genome-scale measures of molecular alterations is of great
interest to researchers aiming to better define disease processes or identify novel targets …
interest to researchers aiming to better define disease processes or identify novel targets …
Statistical approaches for the analysis of DNA methylation microarray data
KD Siegmund - Human genetics, 2011 - Springer
Following the rapid development and adoption in DNA methylation microarray assays, we
are now experiencing a growth in the number of statistical tools to analyze the resulting …
are now experiencing a growth in the number of statistical tools to analyze the resulting …
[HTML][HTML] DNA methylation alterations across time and space in paediatric brain tumours
A Wenger, S Ferreyra Vega, E Schepke… - Acta Neuropathologica …, 2022 - Springer
DNA methylation is increasingly used for tumour classification and has expanded upon the>
100 currently known brain tumour entities. A correct diagnosis is the basis for suitable …
100 currently known brain tumour entities. A correct diagnosis is the basis for suitable …
Array-based analysis of genomic DNA methylation patterns of the tumour suppressor gene p16 INK4A promoter in colon carcinoma …
C Mund, V Beier, P Bewerunge, M Dahms… - Nucleic acids …, 2005 - academic.oup.com
Aberrant DNA methylation at CpG dinucleotides can result in epigenetic silencing of tumour
suppressor genes and represents one of the earliest events in tumourigenesis. To date …
suppressor genes and represents one of the earliest events in tumourigenesis. To date …
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
M Weber, JJ Davies, D Wittig, EJ Oakeley, M Haase… - Nature …, 2005 - nature.com
Cytosine methylation is required for mammalian development and is often perturbed in
human cancer. To determine how this epigenetic modification is distributed in the genomes …
human cancer. To determine how this epigenetic modification is distributed in the genomes …
Application of microarrays for DNA methylation profiling
A Schumacher, A Weinhäusl, A Petronis - Genomics Protocols, 2008 - Springer
Comprehensive analyses of the human epigenome may be of critical importance in
understanding the molecular mechanisms of complex diseases, development, aging, tissue …
understanding the molecular mechanisms of complex diseases, development, aging, tissue …
[HTML][HTML] A cross-package Bioconductor workflow for analysing methylation array data
Methylation in the human genome is known to be associated with development and disease.
The Illumina Infinium methylation arrays are by far the most common way to interrogate …
The Illumina Infinium methylation arrays are by far the most common way to interrogate …