Cortical DNA methylation maintains remote memory

CA Miller, CF Gavin, JA White, RR Parrish… - Nature …, 2010 - nature.com
… cellular memory throughout … of methylation 1 month after learning disrupted remote memory.
We propose that the adult brain utilizes DNA methylation to preserve long-lasting memories. …

DNA methylation in memory formation: emerging insights

FD Heyward, JD Sweatt - The Neuroscientist, 2015 - journals.sagepub.com
… avenues for future inquiry into the role of DNA methylation during remote memory formation.
… expression that underlie memory formation. This review will introduce DNA methylation as a …

DNA methylation: a permissive mark in memory formation and maintenance

AMM Oliveira - Learning & Memory, 2016 - learnmem.cshlp.org
… At 4 wk after training, a time point that corresponds to remote memory, DNA methylation
changes are still present in the ACC, but not in the hippocampus. Moreover, in the ACC, genes …

DNA methylation and memory formation

JJ Day, JD Sweatt - Nature neuroscience, 2010 - nature.com
… Moreover, remote (very long lasting) memory for contextual fear conditioning can be reversed
by infusion of DNMT inhibitors into the anterior cingulate cortex, indicating that ongoing …

The mysteries of remote memory

Z Albo, J Gräff - … Transactions of the Royal Society B …, 2018 - royalsocietypublishing.org
DNA methylation, a mainly … of the DNA, called CpG islands. Through gene-specific analysis
of CpG islands in the promoter region of calcineurin and reelin, cortical DNA methylation has …

DNA methylation and establishing memory

C Bernstein - Epigenetics Insights, 2022 - journals.sagepub.com
… ” that identified cytosine methylation changes at specific … -lived DNA methylation within the
hippocampus for memory … mediated long-lasting memory storage in methylated DNA. By 2016, …

[HTML][HTML] DNA methylation-mediated control of learning and memory

NK Yu, SH Baek, BK Kaang - Molecular brain, 2011 - Springer
… weeks, so that the remote memory becomes dependent on the … test whether memory
maintenance requires DNA methylation, … , DNA methylation on CaN decreased and 30-day …

Drugging the methylome: DNA methylation and memory

AJ Kennedy, JD Sweatt - Critical reviews in biochemistry and …, 2016 - Taylor & Francis
… The erasure of the remote memory trace in the anterior cingulate cortex by DNMT inhibition
… destabilized, and the dynamics of DNA methylation in memory circuits may function as a …

DNA methylation patterns and epigenetic memory

A Bird - Genes & development, 2002 - genesdev.cshlp.org
… of methylation states and the secondary nature of the decision to invite or exclude methylation
support the idea that DNA methylation is adapted for a specific cellular memory function in …

Noradrenergic activation of the basolateral amygdala maintains hippocampus-dependent accuracy of remote memory

E Atucha, V Vukojevic, RV Fornari… - Proceedings of the …, 2017 - National Acad Sciences
… Additionally, to examine if DNA methylation could be associated … of memory-associated
genes, we measured DNA methylation of the Reln and Pkmζ promoters at the recent and remote