Sequence determinants, function, and evolution of CpG islands

A Angeloni, O Bogdanovic - Biochemical Society Transactions, 2021 - portlandpress.com
… a globally hypermethylated state are CpG-rich DNA sequences called CpG islands (CGIs),
which … by DNA sequence features that include DNA hypomethylation, elevated CpG and GC …

Epigenomics: beyond CpG islands

MJ Fazzari, JM Greally - Nature Reviews Genetics, 2004 - nature.com
… We look critically at CpG island biology in the context of the more detailed genome sequence
Determinants of CpG islands: expression in early embryo and isochore structure. Genome …

Synthetic CpG islands reveal DNA sequence determinants of chromatin structure

E Wachter, T Quante, C Merusi, A Arczewska, F Stewart… - Elife, 2014 - elifesciences.org
… a CpG island. Researchers have previously shown that the chromatin of CpG islands has two
… However, the features of the DNA sequence in these CpG islands that are important for this …

Determinants of CpG islands: expression in early embryo and isochore structure

L Ponger, L Duret, D Mouchiroud - Genome research, 2001 - genome.cshlp.org
… In an attempt to understand the origin of CpG islands (CGIs) in mammalian genomes, we
have studied their location and structure according to the expression pattern of genes and to …

[HTML][HTML] CpG Islands shape the epigenome landscape

C Papin, S Le Gras, A Ibrahim, H Salem… - Journal of molecular …, 2021 - Elsevier
… CGIs boundaries, but not transcriptional activity, are essential determinants of H2A.Z …
Therefore, the underlying DNA sequence, the promoter CpG density and, to a lesser extent, …

[HTML][HTML] CpG islands–'a rough guide'

RS Illingworth, AP Bird - FEBS letters, 2009 - Elsevier
… to thymine resulting in the under representation of CpG (21% of that expected in the human
sequences called CpG islands (CGIs) which have an elevated G + C content and little CpG

Identifying CpG islands by different computational techniques

B Hutter, M Paulsen, V Helms - OMICS A Journal of Integrative …, 2009 - liebertpub.com
CpG islands were determined with five different approaches. For the traditional sliding window
method implemented in the CpG IslandDeterminants of CpG islands: expression in early …

Structure, function and evolution of CpG island promoters

F Antequera - Cellular and Molecular Life Sciences CMLS, 2003 - Springer
… have refined our understanding of how CpG island pro- … with CpG islands are CpG deficient
in the corresponding mouse orthologues [3, 33]. The presence or absence of CpG islands at …

Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale

V Barrera, MA Peinado - Nucleic acids research, 2012 - academic.oup.com
… To get insights into the putative determinants of the atypical methylation in discordant HpaII
… of the CpG island, CpG island length, total number of CpG positions in the CpG island and …

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

JP Thomson, PJ Skene, J Selfridge, T Clouaire, J Guy… - Nature, 2010 - nature.com
CpG density destroy the immunity of a CpG island to DNA methylation 25,26 . It follows that
H3K4 methylation due to CpG … genetic and epigenetic determinants of chromosome function. …