Signaling epigenetics: novel insights on cell signaling and epigenetic regulation

RG Arzate‐Mejía, D Valle‐García… - IUBMB life, 2011 - Wiley Online Library
… We have given some examples about how signaling pathways use the epigenetic
machinery to regulate gene expression, and also we have discussed some examples in which …

Epigenetic regulation of cell signaling pathways in acute lymphoblastic leukemia

E San Jose-Eneriz, X Agirre, P Rodriguez-Otero… - …, 2013 - Taylor & Francis
Epigenetic mechanisms, which include DNA methylation and histone … regulation during
many key biological processes. Here, we review the cell signaling pathways that are regulated

Epigenetic regulation of signaling pathways in cancer: role of the histone methyltransferase EZH2

DPF Tsang, ASL Cheng - Journal of gastroenterology and …, 2011 - Wiley Online Library
… causal role for EZH2 in concordant epigenetic regulation of two prominent oncogenic
pathways, thus establishing an oncogene-tumor suppressor-signaling cascade in the promotion of …

Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia

J Román-Gómez, L Cordeu, X Agirre… - Blood, 2007 - ashpublications.org
… The findings described in our study demonstrate that epigenetic regulation of Wnt inhibitors
is another mechanism that significantly contributes to activation of the Wnt-signaling in ALL. …

Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways

A Riccio - Nature neuroscience, 2010 - nature.com
The development and function of neurons require the regulated expression of large numbers
of very specific gene sets. Epigenetic modifications of both DNA and histone proteins are …

Wnt signaling pathway in osteoporosis: Epigenetic regulation, interaction with other signaling pathways, and therapeutic promises

F Amjadi‐Moheb… - Journal of Cellular …, 2019 - Wiley Online Library
… factors and their interaction with other master signaling pathways such as TGF-β, BMP, PI3K/…
of Wnt signaling-related epigenetic regulation, different signaling pathways interacting with …

[HTML][HTML] Cancer signaling pathways with a therapeutic approach: An overview in epigenetic regulations of cancer stem cells

AA Samadani, SE Norollahi, A Rashidy-Pour… - Biomedicine & …, 2018 - Elsevier
… roles of epigenetic regulations in cancer development.Considerably, epigenetic regulations
of gene … Meaningly, recent and novel findings have described the significance of epigenetic

Hedgehog signaling pathway: Epigenetic regulation and role in disease and cancer development

S Fattahi, M Pilehchian Langroudi… - Journal of Cellular …, 2018 - Wiley Online Library
… Aberrant activation of this signaling pathway may occur in a wide … Hh signaling pathway
and provide recent advances on the molecular mechanisms that regulate Hh signaling pathway

Epigenetic regulation of the Wnt/β-catenin signaling pathway in cancer

A Sharma, R Mir, S Galande - Frontiers in genetics, 2021 - frontiersin.org
regulation of the Wnt signaling pathway in various cancer types, with a special emphasis on
the crosstalk with the epigenetic … , the Wnt signaling pathway components are dysregulated …

SMYD3: an oncogenic driver targeting epigenetic regulation and signaling pathways

C Bottino, A Peserico, C Simone, G Caretti - Cancers, 2020 - mdpi.com
… These evidences depict SMYD3 as a modulator of the transcriptional response and of
key signaling pathways, orchestrating multiple oncogenic inputs and ultimately, promoting …