… conserved methyl-CpG binding domains (MBDs). Mutations in the MBD protein MeCP2
cause the neurodevelopmental disease Rett syndrome. We report here the solution structure of …

… Here we describe the solution structure of MBD1 MBD. Based on the structure and results of
… -directed mutagenesis, we identified residues that are critical for binding to methylated CpG. …

… basis of nonmethyl-CpG DNA recognition, we have determined the solution structure of the
MLL … These studies provide a structural basis for understanding how vertebrates interpret the …

… in solution containing a single methyl CpG dinucleotide.(7) The assignment of key residues
within the MeCP2 MBD as crucial for either structural … (14) In solution assays, chicken MeCP2 …

… a 0.5 mM dodecamer duplex solution and a reservoir solution, 50 mM sodium cacodylate
buffer (pH 6), 0.5 mM spermine, 7 mM magnesium acetate and 30% 2‐methyl 2,4‐pentanediol. …

… Solution structure of the methyl-CpG binding domain of human MBD1 in complex with …
Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated …

… Solution structure of MBD4 MBD bound to methylated DNA We determined the solution
structure of the methyl … a central symmetrically methylated m CpG dinucleotide. This 10 bp DNA …

… contain conserved methyl-CpG binding domains (MBDs) 1 … We have previously determined
the solution structure of the … DNA that contains the symmetric methyl-CpG sequence, and the …

… of the solution structure of the MBD has shed light on the type of interactions between the
MBD motif and a methylated CpG pair. Ohki et al. [18] have characterized the structure of the …

… Methylation of CpG motifs in DNA is involved in the control of gene expression and in …
DNAs that contain CpGs. However, effects of methylation on the DNA structure and dynamics are …