… Somatic cell DNA methylation patterns in mammals are established during embryonic … , de
novo methylation, methylation spreading, methylation blocking, and maintenance methylation. …

… (Wigler et al., 1979b1, and the methylation state of these sequences was examined in host
cells 25 generations later by … We conclude from our studies that DNA methylation is heritable. …

… of DNA methylation at certain somatic cell genes may underlie their expression in low-passage
iPS cells, independent of laboratory-specific variability and reprogramming methods. …

… be heritable changes in DNA methylation, known as epimutations, which may be of particular
significance in somatic cells. Whereas the pattern of DNA methylation is very constant for …

… Here we present genome-wide DNA methylation profiles from mouse stem cells (ES, EG
and TS cells) before and after differentiation, and from somatic tissues (brain, kidney, placenta) …

… in somatic cells in culture suggests that DNA methylation patterns are stable in such lines.
Despite this generalization, alterations in DNA methylation … When tissue cells are first put into …

… epigenetic methylation marks in the germline, here we extend this term to include somatic
epigenetic … How do dividing cells manage to preserve their epigenetic imprints? Loss of …

… sufficient to reprogram somatic cells into pluripotent stem cells has significantly expanded …
DNA methylation during cellular reprogramming. Recent data suggest that DNA methylation is …

… used to partially explain somatic inheritance of epigenetic states. The mechanisms by which
DNA methylation patterns could be inherited through generations of somatic cells were first …

… DNA methylation is one of the epigenetic hallmarks that deter… This review will explore the
critical role that DNA methylation … somatic cells leads to modest changes in DNA methylation at …