… propose that DNA methylation is required for normal gastrulation and subsequent patterning
of … To investigate the possible role of DNA methylation in normal zebrafish development, we …

… exposure scenario, the DNA methylation level of the different … central nervous system and
somite development, respectively. … that modification of DNA methylation patterns induced by IR …

… , and DNA methylation contribute to DNA methylation patterning.… significant hyper methylation
at the 15-17 somite stage … C) Bulk DNA methylation of 15-17 somite embryos with h2afv …

… To investigate whether DNA methylation can modulate LR patterning directly, we injected …
embryos at the 5‐somite stage. The embryos at the 10‐somite stage were mounted in 1% low‐…

… of e9.5 somites, we suggest that some of the methylated clones originated from nonsomitic
… Consistent with its broader expression pattern, we find that Mef2A is expressed in all cells …

… 5 to 20 somite stage corresponding to the level of the enzyme. In the mouse, dramatic methylation
… Specific demethylations then form a terminal methylation pattern which is then clonaly …

… to the initiation of the myogenic transcriptional program in the somites [41, 42]. Although
whole genome methylation patterns have been reported in adult skeletal muscle, this type of …

… somites and were age determined as follows: 10 somites (E15), 20 somites (E16), 25
somites (E16.5), 30 somites … Our results indicate that the main pattern in germline migration is …

… (f) About 30% of zebrafish embryos treated with 5-azacytidine show reduction of the dorsal
axis and abnormal patterning of the somites. Reproduced, with permission, from Dev. Biol. …

… The caudal neural tube referred to the neural tube from somite 22 to 28. The neural crest was
measured … Our observation on a similar pattern of low distribution (to 5-MeC-im) of the DNA …