Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology
RP Talens, DI Boomsma, EW Tobi, D Kremer… - The FASEB …, 2010 - Wiley Online Library
… to perform epigenetic association studies. We characterized features of DNA methylation at
16 … To test whether DNA methylation in blood could mark that in other tissues, we studied …
16 … To test whether DNA methylation in blood could mark that in other tissues, we studied …
Major and essential role for the DNA methylation mark in mouse embryogenesis and stable association of DNMT1 with newly replicated regions
S Takebayashi, T Tamura, C Matsuoka… - Molecular and cellular …, 2007 - Taylor & Francis
… cells revealed that preexisting DNA methylation is a major determinant … stable association
with unmethylated chromatin. Our results reveal essential roles for the DNA methylation mark …
with unmethylated chromatin. Our results reveal essential roles for the DNA methylation mark …
Temporal stability and determinants of white blood cell DNA methylation in the breakthrough generations study
JM Flanagan, MN Brook, N Orr, K Tomczyk… - … Biomarkers & Prevention, 2015 - AACR
… We aimed to identify stable variable methylated probes (VMP), ie, markers that are variable
… reported stable methylation changes associated with smoking in white blood cell (WBC) DNA …
… reported stable methylation changes associated with smoking in white blood cell (WBC) DNA …
DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases
MJ Aryee, W Liu, JC Engelmann, P Nuhn… - Science translational …, 2013 - science.org
… analyses of DNA methylation alterations in lethal metastatic prostate cancer and created DNA
methylation “… We show that somatic DNA methylation alterations, despite showing marked …
methylation “… We show that somatic DNA methylation alterations, despite showing marked …
[HTML][HTML] Long-term temporal stability of peripheral blood DNA methylation profiles in patients with inflammatory bowel disease
… we observed a marked stability of … stable DNA methylation in PBLs obtained from a well-generalizable
cohort of adult patients with IBD with a 7-year median time between collected DNA …
cohort of adult patients with IBD with a 7-year median time between collected DNA …
Heritable DNA methylation marks associated with susceptibility to breast cancer
… tested some of the most heritable methylation marks for association with breast cancer. Note
… , at least partially due to periconceptional environment and is stable for at least 10 years 35 . …
… , at least partially due to periconceptional environment and is stable for at least 10 years 35 . …
Genomic patterns of DNA methylation: targets and function of an epigenetic mark
M Weber, D Schübeler - Current opinion in cell biology, 2007 - Elsevier
… patterns at regulatory regions are generally stable, but a minor subset … DNA methylation on
a genome-wide scale have given new insights into the biological function of DNA methylation …
a genome-wide scale have given new insights into the biological function of DNA methylation …
Factors underlying variable DNA methylation in a human community cohort
… , DNA methylation constitutes a main component of the epigenome, and it is considered the
most stable and accessible epigenetic mark … exploring associations of DNA methylation with …
most stable and accessible epigenetic mark … exploring associations of DNA methylation with …
Seasonal stability and dynamics of DNA methylation in plants in a natural environment
… DNA methylation at cytosine residues is an epigenetic mark that can be maintained through
cell divisions in a wide range of eukaryotic genomes [1]. The previous analyses in diverse …
cell divisions in a wide range of eukaryotic genomes [1]. The previous analyses in diverse …
Biological stability of DNA methylation measurements over varying intervals of time and in the presence of acute stress
… = 192), we report the stability of biological replicates over a variety of … the stability of repeated
DNA methylation measurements. In the absence of acute stress, probes were less stable as …
DNA methylation measurements. In the absence of acute stress, probes were less stable as …
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