[HTML][HTML] DNA methylation in stem cell renewal and multipotency
M Berdasco, M Esteller - Stem cell research & therapy, 2011 - Springer
… stem cells could be restricted by the gain of DNA methylation of self-renewal genes (preventing
the undifferentiated features of stem cells in adult somatic cells) and the DNA methylation…
the undifferentiated features of stem cells in adult somatic cells) and the DNA methylation…
DNA methylation and hydroxymethylation in stem cells
… the function of embryonic stem cells and adult stem cells (such as haematopoietic stem
cells, neural stem cells and germline stem cells), and changes in DNA methylation patterns are …
cells, neural stem cells and germline stem cells), and changes in DNA methylation patterns are …
DNA methylation in embryonic stem cells
G Altun, JF Loring, LC Laurent - Journal of cellular biochemistry, 2010 - Wiley Online Library
… In this review, we will give an overview of the existing methods for studying DNA methylation,
and review the key DNA methylation studies specific to ESCs, with an emphasis on reports …
and review the key DNA methylation studies specific to ESCs, with an emphasis on reports …
[PDF][PDF] DNA methylation dynamics during in vivo differentiation of blood and skin stem cells
… DNA methylation during in vivo differentiation remain underexplored. Here we report high-resolution
DNA methylation maps of adult stem … DNA methylation changes were locus specific …
DNA methylation maps of adult stem … DNA methylation changes were locus specific …
[HTML][HTML] DNA methylation dynamics in human induced pluripotent stem cells over time
K Nishino, M Toyoda, M Yamazaki-Inoue… - PLoS …, 2011 - journals.plos.org
… DNA methylation profiles To investigate the dynamics of DNA methylation in pluripotent
stem cells, we examined 5 ESC lines (HUESCs) [23], [24], 22 iPSC lines, their parent cells and …
stem cells, we examined 5 ESC lines (HUESCs) [23], [24], 22 iPSC lines, their parent cells and …
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer
AE Teschendorff, U Menon, A Gentry-Maharaj… - Genome …, 2010 - genome.cshlp.org
… be reflected in multipotent progenitor and stem cell pools. To this end, we investigated the
DNA methylation profiles of cultured mesenchymal stromal/stem cells (MSC) derived from the …
DNA methylation profiles of cultured mesenchymal stromal/stem cells (MSC) derived from the …
[PDF][PDF] Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives
KL Nazor, G Altun, C Lynch, H Tran, JV Harness… - Cell stem cell, 2012 - cell.com
… For these analyses, we identified 214 CpGs on the 450K DNA Methylation array that had
DNA methylation patterns consistent with gametic imprinting according to patterns observed in …
DNA methylation patterns consistent with gametic imprinting according to patterns observed in …
[PDF][PDF] Dynamic heterogeneity and DNA methylation in embryonic stem cells
… Finally, using perturbations, we observed that DNA methylation modulates the population
fraction of cells in the two states, consistent with reciprocal expression of the methyltransferase …
fraction of cells in the two states, consistent with reciprocal expression of the methyltransferase …
Pluripotent stem cells escape from senescence-associated DNA methylation changes
CM Koch, K Reck, K Shao, Q Lin, S Joussen… - Genome …, 2013 - genome.cshlp.org
… evade replicative senescence, whereas other primary cells lose their … DNA methylation
(SA-DNAm) changes. Here, we investigate SA-DNAm changes in mesenchymal stromal cells (…
(SA-DNAm) changes. Here, we investigate SA-DNAm changes in mesenchymal stromal cells (…
DNA methylation on N6-adenine in mammalian embryonic stem cells
… the only form of DNA methylation in mammalian genomes. Here we identify N 6 -methyladenine
as another form of DNA modification in mouse embryonic stem cells. Alkbh1 encodes a …
as another form of DNA modification in mouse embryonic stem cells. Alkbh1 encodes a …
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