DNA methylation in adult stem cells: New insights into self-renewal
JJ Trowbridge, SH Orkin - Epigenetics, 2010 - Taylor & Francis
… somatic stem cells, regulation of transcription by DNA methylation both … such stability
contributes to stem cell selfrenewal and … cells, recent studies have highlighted a critical role for …
contributes to stem cell selfrenewal and … cells, recent studies have highlighted a critical role for …
Identification of global DNA methylation signatures in glioblastoma-derived cancer stem cells
EJ Lee, P Rath, J Liu, D Ryu, L Pei… - Journal of genetics and …, 2015 - Elsevier
… to the resilient behavior of tumor cells and poor prognosis. In this study, we performed an
in-depth analysis of the DNA methylation landscape in GBM-derived cancer stem cells (GSCs). …
in-depth analysis of the DNA methylation landscape in GBM-derived cancer stem cells (GSCs). …
[HTML][HTML] Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
LM Butcher, M Ito, M Brimpari, TJ Morris… - Nature …, 2016 - nature.com
… stem cells with an impaired differentiation capacity for endodermal lineages exhibit reduced
DNA methylation at … This finding infers non-CG methylation can be used as a biomarker for …
DNA methylation at … This finding infers non-CG methylation can be used as a biomarker for …
The effects of the DNA methyltranfserases inhibitor 5‐Azacitidine on ageing, oxidative stress and DNA methylation of adipose derived stem cells
K Kornicka, K Marycz, M Marędziak… - Journal of Cellular …, 2017 - Wiley Online Library
… results of immunofluorescence methylation staining. Moreover, DNA methylation status was
assessed quantitatively using ELISA test. We observed decreases in DNA methylation after 5…
assessed quantitatively using ELISA test. We observed decreases in DNA methylation after 5…
[HTML][HTML] G9a/GLP complex maintains imprinted DNA methylation in embryonic stem cells
T Zhang, A Termanis, B Özkan, XX Bao, J Culley… - Cell reports, 2016 - cell.com
… Here, we report that pluripotent stem cells null for either G9a or GLP display a widespread
loss of imprinted DNA methylation, which can be reproduced by a small hairpin RNA (shRNA) …
loss of imprinted DNA methylation, which can be reproduced by a small hairpin RNA (shRNA) …
… of the p16INK4A gene is associated closely with senescence of human mesenchymal stem cells and is potentially silenced by DNA methylation during in vitro …
KR Shibata, T Aoyama, Y Shima, K Fukiage… - Stem …, 2007 - academic.oup.com
… The remaining four strains (13.8%) showed different profiles, in which DNA methylation in …
and, most importantly, careful monitoring of DNA methylation should be considered during the …
and, most importantly, careful monitoring of DNA methylation should be considered during the …
[HTML][HTML] DNA methylation profile is associated with the osteogenic potential of three distinct human odontogenic stem cells
T Ai, J Zhang, X Wang, X Zheng, X Qin… - Signal transduction and …, 2018 - nature.com
… -scale DNA methylation … DNA methylation states among three dental stem cell lines. In
addition, we aimed to determine whether the differential methylation profiles of these stem cells …
addition, we aimed to determine whether the differential methylation profiles of these stem cells …
The effect of culture on human bone marrow mesenchymal stem cells: focus on DNA methylation profiles
A Bentivegna, G Roversi, G Riva… - Stem Cells …, 2016 - Wiley Online Library
… DNA methylation (DNAm) patterns were overlapping and … In this work we focused our attention
on DNA methylation … is normally methylated, compared to most genes where the pattern of …
on DNA methylation … is normally methylated, compared to most genes where the pattern of …
DNA methylation profiles define stem cell identity and reveal a tight embryonic–extraembryonic lineage boundary
… endoderm (XEN) stem cells contribute predominantly to … four stem cell types is defined by
a unique DNA methylation profile. Despite their distinct developmental origin, TS and XEN cells …
a unique DNA methylation profile. Despite their distinct developmental origin, TS and XEN cells …
DNA methylation in skeletal muscle stem cell specification, proliferation, and differentiation
RC Laker, JG Ryall - Stem cells international, 2016 - Wiley Online Library
… and in particular DNA methylation, in the regulation of stem cell identity, this … methylation,
with a particular focus on skeletal muscle stem cells (MuSCs, also referred to as satellite cells). …
with a particular focus on skeletal muscle stem cells (MuSCs, also referred to as satellite cells). …