Methylation of FKBP5 and SLC6A4 in Relation to Treatment Response to Mindfulness Based Stress Reduction for Posttraumatic Stress Disorder

JR Bishop, AM Lee, LJ Mills, PD Thuras, S Eum… - Frontiers in …, 2018 - frontiersin.org
methylation biomarker studies. We conducted a pilot study investigating the methylation of
SLC6A4 and FKBP5 … We hypothesized that decreased methylation in SLC6A4 and FKBP5

DNA methylation of NR3C1 and FKBP5 is associated with posttraumatic stress disorder, posttraumatic growth, and resilience.

O Miller, J Shakespeare-Finch, D Bruenig… - … , Practice, and Policy, 2020 - psycnet.apa.org
… We hypothesized that NR3C1 and FKBP5 methylation would … DNA methylation of stress
genes NR3C1 and FKBP5 with the … , methylation of different regions of both NR3C1 and FKBP5

Gene–stress–epigenetic regulation of FKBP5: clinical and translational implications

AS Zannas, T Wiechmann, NC Gassen… - …, 2016 - nature.com
… 7 of the FKBP5 gene that shows reduced methylation with … FKBP5 methylation sites that
appears to occur across peripheral and neuronal tissues and to depend on susceptible FKBP5

Reduced DNA methylation of FKBP5 in Cushing's syndrome

E Resmini, A Santos, A Aulinas, SM Webb… - Endocrine, 2016 - Springer
… We aimed at evaluating blood DNA methylation of FKBP5 and its relationship … FKBP5 has
also been assessed to determine whether genetic variations can also govern CpG methylation. …

Allele-specific DNA methylation level of FKBP5 is associated with post-traumatic stress disorder

JI Kang, TY Kim, JH Choi, HS So, SJ Kim - Psychoneuroendocrinology, 2019 - Elsevier
… The present study demonstrated different FKBP5 methylation levels in PTSD depending
on FKBP5 genetic variation among veterans exposed to combat trauma. The present finding …

Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency

JJ Sabbagh, JC O'Leary III, LJ Blair, T Klengel… - PloS one, 2014 - journals.plos.org
… We also found that methylation of Fkbp5 decreased with age in mice, a process that likely
explains the age-associated increases in FKBP51 levels. Thus, epigenetic upregulation of …

Childhood maltreatment and methylation of FK506 binding protein 5 gene (FKBP5)

AR Tyrka, KK Ridout, SH Parade… - Development and …, 2015 - cambridge.org
… alters its ability to respond to stress signaling. The aim of the present study was to examine
methylation of the FKBP5 gene (FKBP5), and the role of an FKBP5 genetic variant, in relation …

DNA methylation of FKBP5 and response to exposure‐based psychological therapy

S Roberts, R Keers, G Breen… - American Journal of …, 2019 - Wiley Online Library
… changes in DNA methylation at FKBP5 intron 7 associated with reduction in anxiety
severity following exposure-based CBT. We also observed allele-specific methylation at the …

Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk

AS Zannas, M Jia, K Hafner… - Proceedings of the …, 2019 - National Acad Sciences
… S5), we speculated that methylation at the age/stress-related FKBP5 … age/stress-related
decrease in FKBP5 methylation can enhance transcription factor binding and consequent FKBP5

[HTML][HTML] Developmental exposure to bisphenol A alters expression and DNA methylation of Fkbp5, an important regulator of the stress response

E Kitraki, I Nalvarte, A Alavian-Ghavanini… - Molecular and cellular …, 2015 - Elsevier
Fkbp5 in hypothalamus and hippocampus of exposed offspring. We found increased DNA
methylation of Fkbp5 and reduced … -down affected Fkbp5 expression and methylation similarly …